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酪氨酸酶

酪氨酸酶用途

酪氨酸酶(多酚氧化酶)是一种控制黑色素生成的限速酶,由TYR基因编码。酪氨酸酶主要存在于皮肤黑素细胞合成的黑素体中[1]。

酪氨酸酶名称

[ CAS 号 ]:
9002-10-2

[ 中文名 ]:
酪氨酸酶

[ 英文名 ]:
TYROSINASE

[英文别名 ]:

EINECS 232-653-4

酪氨酸酶生物活性

[ 描述 ]:

酪氨酸酶(多酚氧化酶)是一种控制黑色素生成的限速酶,由TYR基因编码。酪氨酸酶主要存在于皮肤黑素细胞合成的黑素体中[1]。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 酪氨酸酶

研究领域 >> 代谢疾病

[参考文献]

[1]. Sánchez-Ferrer A, et al. Tyrosinase: a comprehensive review of its mechanism. Biochim Biophys Acta. 1995 Feb 22;1247(1):1-11.

酪氨酸酶物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
1578.2±65.0 °C at 760 mmHg

[ 分子式 ]:
C₄₂H₆₆N₁₀O₁₆S₂

[ 分子量 ]:
1031.161

[ 闪点 ]:
908.2±34.3 °C

[ 精确质量 ]:
1030.409912

[ LogP ]:
-1.38

[ 外观性状 ]:
lyophilized powder

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.590

[ 储存条件 ]:
−20°C

酪氨酸酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
42

[ 安全声明 (欧洲) ]:
22-24/25-45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

酪氨酸酶文献

Separation of the antioxidant compound quercitrin from Lindera obtusiloba Blume and its antimelanogenic effect on B16F10 melanoma cells.

Biosci. Biotechnol. Biochem. 77(1) , 58-64, (2013)

Considering the growing evidence of the presence of antioxidant compounds in plant extracts, the objectives of this study were to identify antioxidant compounds in Lindera obtusiloba Blume (Lauraceae)...

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res. 14 , 2121-7, (2004)

The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for...

Standardised herbal extract of chlorogenic acid from leaves of Etlingera elatior (Zingiberaceae).

Pharmacognosy Res. 3 , 178-184, (2011)

Chlorogenic acid (CGA) or 5-caffeoylquinic acid, was found to be the dominant phenolic compound in leaves of Etlingera elatior (Zingiberaceae). The CGA content of E. elatior leaves was significantly h...

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