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促肾上腺皮质激素释放激素

促肾上腺皮质激素释放激素用途

促肾上腺皮质激素释放激素(CRH)是一种参与应激反应的肽激素。促肾上腺皮质激素释放因子(CRF)是应激条件下下丘脑-垂体-肾上腺(HPA)轴的主要调节肽。促肾上腺皮质激素释放激素(CRH)可用于神经内分泌和焦虑样行为的研究[1][2]。

促肾上腺皮质激素释放激素名称

[ CAS 号 ]:
9015-71-8

[ 中文名 ]:
促肾上腺皮质激素释放激素

[ 英文名 ]:
Corticotropin Releasing Factor (148-188), ovine

[英文别名 ]:

SQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIA-NH2
Corticotropin Releasing Factor (148-188), ovine

促肾上腺皮质激素释放激素生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

促肾上腺皮质激素释放激素物理化学性质

[ 分子式 ]:
C₂₀₅H₃₃₉N₅₉O₆₃S

[ 分子量 ]:
4670.38

[ 储存条件 ]:
-20°C

促肾上腺皮质激素释放激素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3.0

促肾上腺皮质激素释放激素文献

Neurokinin B signaling in the female rat: a novel link between stress and reproduction.

Endocrinology 155(7) , 2589-601, (2014)

Acute systemic stress disrupts reproductive function by inhibiting pulsatile gonadotropin secretion. The underlying mechanism involves stress-induced suppression of the GnRH pulse generator, the funct...

Expression and regulation of neuromedin B in pituitary corticotrophs of male melanocortin 2 receptor-deficient mice.

Endocrinology 155(7) , 2492-9, (2014)

The hypothalamic-pituitary-adrenal (HPA) axis is a major part of the neuroendocrine system that controls responses to stress, and has an important function in the regulation of various body processes....

Bisphenol A differentially activates protein kinase C isoforms in murine placental tissue

Toxicol. Appl. Pharmacol. 269(2) , 163-8, (2013)

Bisphenol A is utilized to make polycarbonate plastics and is an environmental pollutant. Recent research has indicated that it is an endocrine disruptor and may interfere with reproductive processes....

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