4-羟基苯甲酸苯甲酯

4-羟基苯甲酸苯甲酯用途

4-羟基苯甲酸苄酯是一种突出的材料。4-羟基苯甲酸苄酯可用作辅料,如抑菌剂、防腐剂等。药用辅料,或称药用辅料,是指除药物成分外,在制药过程中使用的其他化学物质。药用辅料一般是指药物制剂中的非活性成分,可以提高药物制剂的稳定性、溶解性和加工性。药用辅料也会影响联合给药药物的吸收、分布、代谢和消除(ADME)过程[1][2]。

4-羟基苯甲酸苯甲酯名称

[ CAS 号 ]:
94-18-8

[ 中文名 ]:
4-羟基苯甲酸苄酯

[ 英文名 ]:
Benzylparaben

[中文别名 ]:

[英文别名 ]:

Benzyl 4-hydroxybenzoate
BASEPTOL
Benzoic acid, 4-hydroxy-, phenylmethyl ester
MFCD00016471
Benzylparaben
EINECS 202-311-9
PARABEN,BENZYL
4-Hydroxybenzoic acid benzyl ester
Benzoic acid, p-hydroxy-, benzyl ester (8CI)
Benzyl parabe

4-羟基苯甲酸苯甲酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Solanki S S B, et al. Growth and characterization of benzyl 4-hydroxybenzoate single crystal by vertical Bridgman technique for optical applications[J]. Optics & Laser Technology, 2018, 103: 163-169.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

4-羟基苯甲酸苯甲酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
389.8±17.0 °C at 760 mmHg

[ 熔点 ]:
109-112 °C(lit.)

[ 分子式 ]:
C₁₄H₁₂O₃

[ 分子量 ]:
228.25

[ 闪点 ]:
168.0±13.7 °C

[ 精确质量 ]:
228.078644

[ PSA ]:
46.53000

[ LogP ]:
3.64

[ 外观性状 ]:
白色至淡黄色细粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.607

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
可溶于：甲醇

4-羟基苯甲酸苯甲酯MSDS

4-羟基苯甲酸苯甲酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DH2691000

[ 海关编码 ]:
2918290000

4-羟基苯甲酸苯甲酯合成路线

4-羟基苯甲酸苯甲酯上下游产品

4-羟基苯甲酸苯甲酯上游产品

4-羟基苯甲酸苯甲酯下游产品

4-羟基苯甲酸苯甲酯海关

[ 海关编码 ]: 2918290000

[ 中文概述 ]:
2918290000 其他含酚基但不含其他含氧基羧酸及其酸酐、酰卤化物、过氧化物和过氧酸及它们的衍生物。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

4-羟基苯甲酸苯甲酯文献

Analysis of endocrine disrupters and related compounds in sediments and sewage sludge using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1352 , 29-37, (2014)

A novel fully automated method based on dual column switching using turbulent flow chromatography followed by liquid chromatography coupled to tandem mass spectrometry (TFC-LC-MS/MS) was applied for t...

Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatography tandem mass spectrometry analysis.

J. Chromatogr. A. 1355 , 26-35, (2014)

Pharmaceutical and personal care products (PPCPs) are one of the most important classes of emerging contaminants. The potential of ecological and environmental impacts associated with PPCPs are of par...

Fast and simultaneous determination of endocrine disrupting compounds by ultra-high performance liquid chromatography-tandem mass spectrometry.

Talanta 146 , 326-34, (2015)

A rapid and sensitive analytical method for the simultaneous determination of thirteen endocrine disruptors (five phthalates, seven parabens, and bisphenol A) in a single chromatographic run has been ...

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