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N-十二烷酰基肌氨酸

N-十二烷酰基肌氨酸用途

N-月桂酰肌氨酸(NLS)是一种阴离子表面活性剂,可用作渗透促进剂。NLS在25–50%乙醇中的混合物具有协同作用,可增加皮肤渗透性,这可能有助于透皮给药研究[1]。

N-十二烷酰基肌氨酸名称

[ CAS 号 ]:
97-78-9

[ 中文名 ]:
N-月桂酰肌氨酸

[ 英文名 ]:
N-LAUROYLSARCOSINE

[中文别名 ]:

[英文别名 ]:

EINECS 202-608-3
MFCD00021749
n-lauroylsarcosine

N-十二烷酰基肌氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Yeu-Chun Kim, et al. Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol. Int J Pharm. 2008 Mar 20;352(1-2):129-38.

N-十二烷酰基肌氨酸物理化学性质

[ 密度 ]:
0.986g/cm3

[ 沸点 ]:
413.2ºC at 760mmHg

[ 熔点 ]:
45-49 °C

[ 分子式 ]:
C₁₅H₂₉NO₃

[ 分子量 ]:
271.39600

[ 精确质量 ]:
271.21500

[ PSA ]:
57.61000

[ LogP ]:
3.45030

[ 外观性状 ]:
固体;White or Colorless to Almost white or Almost colorless powder to lump to clear liquid

[ 储存条件 ]:
0-10°C;存放于惰性气体之中;避免湿气 (分解)

N-十二烷酰基肌氨酸MSDS

N-十二烷酰基肌氨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
2811.0

[ WGK德国 ]:
1

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2924199090

N-十二烷酰基肌氨酸合成路线

N-十二烷酰基肌氨酸上下游产品

N-十二烷酰基肌氨酸上游产品

N-十二烷酰基肌氨酸下游产品

N-十二烷酰基肌氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-十二烷酰基肌氨酸文献

Molecular characterisation of clinical and environmental isolates of Mycobacterium kansasii isolates from South African gold mines.

J. Water Health 13 , 190-202, (2015)

Mycobacterium kansasii (M. kansasii) is a major cause of non-tuberculous mycobacterial pulmonary disease in the South African gold-mining workforce, but the source of infection and molecular epidemiol...

Improved enrichment and proteomic identification of outer membrane proteins from a Gram-negative bacterium: focus on Caulobacter crescentus.

Proteomics 12(2) , 251-62, (2012)

Efforts to characterize proteins found in the outer membrane (OM) of Gram-negative bacteria have been steadily increasing due to the promise of expanding our understanding of fundamental bacterial pro...

Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents.

Soft Matter 11 , 6840-51, (2015)

Most antimicrobial peptides act upon target microorganisms by permeabilizing their membranes. The mode of action is often assessed by vesicle leakage experiments that use model membranes, with the ass...

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