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上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：磺胺噁唑
纯度：98.0%
规格：
联系人：徐经理
联系电话：13311869306

上海源溪生物科技有限公司
上海市上海市浦东新区
产品名：NSC683535
纯度：98.9%
规格：1g
联系人：赖经理
联系电话：13564518121

上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：磺胺二甲基恶唑
纯度：98.0%
规格：100mg/25mg/1g/1g
联系人：阿拉丁
联系电话：400-620-6333

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729-99-7生产厂家

729-99-7

729-99-7结构式

常用中文名：磺胺二甲唑
常用英文名：sulfamoxol
CAS号：729-99-7
分子式：C₁₁H₁₃N₃O₃S
分子量：267.30400
相关类别：分析化学标准品法医和兽医标准品
发布时间：2018-05-23 08:00:00
更新时间：2024-01-02 16:08:08
Sulfamoxole 是一种广谱化疗抗菌(antimicrobial agent) 试剂。Sulfamoxole 可用于小儿感染的相关研究。

化源商城直购

中文名	磺胺二甲唑
英文名	sulfamoxole
中文别名	磺胺二甲恶唑磺胺噁唑
英文别名	SULFAMOXOLE Sulfamoxol 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide Sulphamoxole Sulfavigor sulphamoxazole Oxasulfa Sulfmidil Sulfadimethyloxazole Sulfamoxolum Justamil sulfisoxazole Sulfuno

描述	Sulfamoxole 是一种广谱化疗抗菌(antimicrobial agent) 试剂。Sulfamoxole 可用于小儿感染的相关研究。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
参考文献	[1]. F Lagler, R Kretzschmar, et al. Toxicological Investigations of the Combination Sulfamoxole/Trimethoprim, a New Broad-Spectrum Chemotherapeutic. Arzneimittelforschung. 1976;26(42):634-43. [2]. J A DUGGER, et al. Sulfamoxole (Nuprin), a New Sulfonamide, in Pediatric Practice. J New Drugs. Sep-Oct 1961;1:223-9.

密度	1.411g/cm3
沸点	481ºC at 760 mmHg
熔点	197-199℃
分子式	C₁₁H₁₃N₃O₃S
分子量	267.30400
闪点	244.7ºC
精确质量	267.06800
PSA	106.60000
LogP	3.40940
折射率	1.626
储存条件	库房通风低温干燥
计算化学	1.疏水参数计算参考值（XlogP）:1.3 2.氢键供体数量:2 3.氢键受体数量:6 4.可旋转化学键数量:3 5.互变异构体数量:2 6.拓扑分子极性表面积:107 7.重原子数量:18 8.表面电荷:0 9.复杂度:374 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WO9150000

CHEMICAL NAME :: Sulfanilamide, N(sup 1)-(4,5-dimethyl-2-oxazolyl)-

CAS REGISTRY NUMBER :: 729-99-7

LAST UPDATED :: 199706

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C11-H13-N3-O3-S

MOLECULAR WEIGHT :: 267.33

WISWESSER LINE NOTATION :: T5N COJ BMSWR DZ& D1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >12500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,634,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,634,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,612,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,634,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1285 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,612,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,612,1960 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1525 mg/kg/9W-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,617,1960

符号	GHS07
信号词	Warning
危害声明	H317
警示性声明	P280
个人防护装备	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
危害码 (欧洲)	Xi
风险声明 (欧洲)	43
安全声明 (欧洲)	36/37
危险品运输编码	NONH for all modes of transport
RTECS号	WO9150000

45529-92-8结构式

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729-99-7结构式

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110490-38-5结构式

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103640-72-8结构式

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121-60-8结构式

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98-74-8结构式

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