CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XY0700000
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CHEMICAL NAME :
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Triazene, 3,3-dimethyl-1-(p-chlorophenyl)-
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CAS REGISTRY NUMBER :
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7203-90-9
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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C8-H10-Cl-N3
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MOLECULAR WEIGHT :
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183.66
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WISWESSER LINE NOTATION :
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GR DNUNN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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362 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Liver - other changes Blood - changes in cell count (unspecified)
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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330 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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3200 mg/kg/70W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Musculoskeletal - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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300 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors Kidney, Ureter, Bladder - Kidney tumors
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TYPE OF TEST :
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Sex chromosome loss and nondisjunction
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TYPE OF TEST :
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Micronucleus test
MUTATION DATA
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TYPE OF TEST :
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Host-mediated assay
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TEST SYSTEM :
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Rodent - mouse Yeast - Saccharomyces cerevisiae
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DOSE/DURATION :
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73464 mg/kg
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REFERENCE :
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CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 9,365,1974
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