19933-24-5

• 常用中文名：5-(2-噻吩)-1H-吡唑
• 常用英文名：3-(2-thienyl)pyrazole
• CAS号：19933-24-5
• 分子式：C₇H₆N₂S
• 分子量：150.20100
• 发布时间：2018-04-05 08:00:00
• 更新时间：2024-01-11 10:27:57
• 下载msds

名称

• 中文名: 3-(2-噻吩)吡唑
• 英文名: 5-thiophen-2-yl-1H-pyrazole
• 中文别名: 3-(2-噻吩基)吡唑; 5-(2-噻吩)-1H-吡唑
• 英文别名: MFCD00178757; 3-thiophen-2-yl-1h-pyrazole; 3-(2-THIENYL)PYRAZOLE; 2-pyrazol-3-ylthiophene

物化性质

• 密度: 1.297g/cm3
• 沸点: 152 °C (1.6 mmHg)
• 熔点: 97-99 °C
• 分子式: C₇H₆N₂S
• 分子量: 150.20100
• 闪点: 143.4ºC
• 精确质量: 150.02500
• PSA: 56.92000
• LogP: 2.13820
• 外观性状: 淡绿色细松软的粉末
• 蒸汽压: 0.00139mmHg at 25°C
• 折射率: 1.641
• 储存条件:

  在密封的贮藏器内，并放置阴凉，干燥的地方保存

• 稳定性:

  如果按照规则使用和储存则不会分解

  避免接触 氧化物
• 分子结构:

  五、分子性质数据：

  1、 摩尔折射率：41.75

  2、 摩尔体积(m³/mol)：115.7

  3、 等张比容(90.2K)：317.5

  4、 表面张力(dyne/cm)：56.6

  5、 极化率(10-24cm³)：16.55

• 计算化学:

  1.疏水参数计算参考值（XlogP）:1.6

  2.氢键供体数量:1

  3.氢键受体数量:2

  4.可旋转化学键数量:1

  5.互变异构体数量:2

  6.拓扑分子极性表面积56.9

  7.重原子数量:10

  8.表面电荷:0

  9.复杂度:118

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1.性状：未确定

  2.密度（g/mL,25/4℃）：未确定

  3.相对蒸汽密度（g/mL,空气=1）：未确定

  4.熔点（ºC ）：97-99

  5.沸点（ºC,常压）：152 °C (1.6 mmHg)

  6.沸点（ºC,5.2kPa）：未确定

  7.折射率：未确定

  8.闪点（ºC）：未确定

  9.比旋光度（º）：未确定

  10.自燃点或引燃温度（ºC）：未确定

  11.蒸气压（kPa,25ºC）：未确定

  12.饱和蒸气压（kPa,60ºC）：未确定

  13.燃烧热（KJ/mol）：未确定

  14.临界温度（ºC）：未确定

  15.临界压力（KPa）：未确定

  16.油水（辛醇/水）分配系数的对数值：未确定

  17.爆炸上限（%,V/V）：未确定

  18.爆炸下限（%,V/V）：未确定

  19.溶解性：未确定

MSDS

Name: 3-(2-Thienyl) Pyrazole 99+% Material Safety Data Sheet Synonym: CAS: 19933-24-5 Section 1 - Chemical Product MSDS Name:3-(2-Thienyl) Pyrazole 99+% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 19933-24-5 3-(2-Thienyl) Pyrazole 99+ unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: No information regarding eye irritation and other potential effects was found. Skin: No information regarding skin irritation and other potential effects was found. Ingestion: The toxicological properties of this substance have not been fully investigated. Inhalation: The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water fog, dry chemical, carbon dioxide, or regular foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a cool, dry place. Keep containers tightly closed. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 19933-24-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: light green Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 152 deg C @ 1.60mmHg Freezing/Melting Point: 97.00 - 98.00 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H6N2S Molecular Weight: 150.20 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Not available. Incompatibilities with Other Materials: Strong oxidizing agents, strong bases. Hazardous Decomposition Products: Not available. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 19933-24-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 3-(2-Thienyl) Pyrazole - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 19933-24-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 19933-24-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 19933-24-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微危害的，若无政府许可，勿将材料排入周围环境

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S37/39-S24/25
• 海关编码: 2934999090

合成路线

34772-98-0 ~69% 19933-24-5

文献：Al-Omran, Fatima; Al-Awadi, Nouria; El-Khair, Adel Abou; Elnagdi, Mohammed Hilmy Organic Preparations and Procedures International, 1997 , vol. 29, # 3 p. 285 - 292

98-03-3 ~% 19933-24-5

文献：Tetrahedron Letters, , vol. 39, # 20 p. 3287 - 3290

88-15-3 ~% 19933-24-5

文献：Organic Preparations and Procedures International, , vol. 29, # 3 p. 285 - 292

221235-30-9 ~% 19933-24-5 41078-15-3

文献：Journal of Chemical Research, Miniprint, , # 1 p. 151 - 163

上下游产品

上游产品  4
34772-98-0 98-03-3 88-15-3 221235-30-9
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%