198220-53-0
198220-53-0结构式
- 常用中文名：4-(2,6-二甲基苯胺)-4-氧代-2-丁酸
- 常用英文名：4-(2,6-dimethylanilino)-4-oxobut-2-enoic acid
- CAS号：198220-53-0
- 分子式：C12H13NO3
- 分子量：219.23700
- 发布时间：2018-11-28 17:41:25
- 更新时间：2024-01-09 18:29:19
| 中文名 | 4-(2,6-二甲基苯胺)-4-氧代-2-丁酸 |
|---|---|
| 英文名 | 4-(2,6-dimethylanilino)-4-oxobut-2-enoic acid |
| 密度 | 1.243g/cm3 |
|---|---|
| 沸点 | 436.3ºC at 760 mmHg |
| 熔点 | 169ºC |
| 分子式 | C12H13NO3 |
| 分子量 | 219.23700 |
| 闪点 | 217.6ºC |
| 精确质量 | 219.09000 |
| PSA | 66.40000 |
| LogP | 1.95570 |
| 蒸汽压 | 2.21E-08mmHg at 25°C |
| 折射率 | 1.609 |
Synonym:N-(2,6-Dimethylphenyl)maleamic aci Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 198220-53-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 169 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H13NO3 Molecular Weight: 219 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 198220-53-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-(2,6-Dimethylanilino)-4-oxobut-2-enoic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 198220-53-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 198220-53-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 198220-53-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi:Irritant; |
|---|---|
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | S26-S37/39 |
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198220-53-0 |
| 文献：Salewska, Natalia; Boros-Majewska, Joanna; Lcka, Izabela; Chylinska, Katarzyna; Sabisz, Michal; Milewski, Slawomir; Milewska, Maria J. Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 1 p. 117 - 124 |
