56-36-0

• 常用中文名：三正丁基乙酸锡
• 常用英文名：tri-n-butyltin acetate
• CAS号：56-36-0
• 分子式：C₁₄H₃₀O₂Sn
• 分子量：349.08800
• 相关类别： 有机原料 有机金属类化合物 有机锡
• 发布时间：2018-09-21 11:34:52
• 更新时间：2024-01-10 12:18:43

名称

• 中文名: 三正丁基乙酸锡
• 英文名: tributylstannyl acetate
• 中文别名: 醋酸三丁锡
• 英文别名: Stannane,(acetyloxy)tributyl; tributyltin acetate; (acetyloxy)tributyl-stannane; Stannane,acetoxytributyl; MFCD00015228; Acetoxytributyltin; EINECS 200-269-6; Tributylacetoxystannane; Tin,acetoxytributyl; tin tributylacetate; Tribuyltin acetate; Tri-n-butyltin acetate; Acetoxytributylstannane

物化性质

• 密度: 1,27 g/cm3
• 沸点: 120 °C / 2mmHg
• 熔点: 80-83 °C(lit.)
• 分子式: C₁₄H₃₀O₂Sn
• 分子量: 349.08800
• 闪点: 120 °C
• 精确质量: 350.12700
• PSA: 26.30000
• LogP: 4.89530
• 储存条件: 库房低温,通风,干燥,与食品原料分开存放
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:2

  4.可旋转化学键数量:11

  5.互变异构体数量:无

  6.拓扑分子极性表面积26.3

  7.重原子数量:17

  8.表面电荷:0

  9.复杂度:183

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

MSDS

Section 1: Product Identification Chemical Name:Tri-n-butyltin acetate, 98% CAS Registry Number:56-36-0 Formula:(C4H9)3SnOOCCH3 EINECS Number:200-269-6 Chemical Family:organotin compound Synonym:Acetoxytributylstanne, Tributylstannyl acetate, Tri-n-butyltin acetate Section 2: Composition and Information on Ingredients IngredientCAS NumberPercentACGIH (TWA)OSHA (PEL) Title Compound56-36-0100%0.1mg/m30.1mg/m3 Section 3: Hazards Identification Organo tin compounds may act as delayed poisons, causing headache, dizziness; psycho-neurologic Emergency Overview: disturbances; sore throat, vomiting; urine retention; vision impairment; skin burns, liver and kidney damage. Primary Routes of Exposure:Ingestion, inhalation, skin, eyes Eye Contact:Causes irritation of the eyes. Skin Contact:Causes irritation of the skin. Prolonged contact may dry the skin and lead to rashes or more severe irritation. Irritating to the nose, mucous membranes and respiratory tract. High doses may cause long term neurological Inhalation: damage. Delayed and permanent psycho-neurologic disturbances; impairment of vision, unsteadiness, nausea and Ingestion: vomiting. Toxic if swallowed. Irritating to skin, eyes and mucous membranes. Ingestion of certain organotin compounds may cause delayed Acute Health Affects: poisoning (4 days) with cerebral edema causing damage to the central nervous system. Repeated exposure to certain organic tin compounds may cause problems with vision, skin, respiratory Chronic Health Affects: system, central nervous system, liver, kidneys, urinary tract, and blood. NTP:No IARC:No OSHA:No SECTION 4: First Aid Measures Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need Eye Exposure: assistance in keeping their eye lids open. Get immediate medical attention. Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if Skin Exposure: irritation persists. Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty Inhalation: in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce Ingestion: vomiting only if directed by medical personnel. SECTION 5: Fire Fighting Measures Flash Point:no data Autoignition Temperature:no data Explosion Limits:no data Extinguishing Medium:carbon dioxide or dry powder Fire fighters should be equipped with a NIOSH approved positive pressure self-contained breathing apparatus Special Fire Fighting Procedures: and full protective clothing. Hazardous Combustion andcarbon monoxide, carbon dioxide, soot, organic fumes and tin compounds. Decomposion Products: Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards. SECTION 6: Accidental Release Measures Small spills can be mixed with vermiculite, ground limestone, sodium carbonate or other suitable Spill and Leak Procedures: noncombustible adsorbent and swept up. SECTION 7: Handling and Storage Handling and Storage:Store in a cool, dry, well ventilated area away from heat and direct sunlight. Keep containers tightly sealed. SECTION 8: Exposure Controls and Personal Protection Eye Protection:Always wear approved safety glasses when handling a chemical substance in the laboratory. Skin Protection:Wear protective clothing and gloves. Consult with glove manufacturer to determine the proper type of glove. Ventilation:Work with this product in a well-ventilated area, preferably a fume hood. If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Respirator: Protection Program to be in compliance with 29 CFR 1910.134. Ventilation:Work with this product in a well-ventilated area, preferably a fume hood. Additional Protection:No additional protection required. SECTION 9: Physical and Chemical Properties Color and Form:white pwdr. Molecular Weight:349.08 Melting Point:87° Boiling Point:no data Vapor Pressure:no data Specific Gravity:1.27 Odor:not determined Solubility in Water:insoluble SECTION 10: Stability and Reactivity Stability:moisture sensitive Hazardous Polymerization:no hazardous polymerization Conditions to Avoid:none Incompatibility:strong oxidizing agents and halogens Decomposition Products:carbon monoxide, carbon dioxide, tin oxide, organic fumes. SECTION 11: Toxicological Information Oral (rat); LD50: 99 mg/kg. Intraperitoneal (rat); LDLo: 10 mg/kg. Oral (mouse); LD50: 46 mg/kg. Intravenous (mouse); LD50: 180 mg/kg. Oral (rabbit); LDLo: 40 mg/kg. Oral (guinea pig); LDLo: 20 mg/kg. Administration RTECS Data:onto the skin (mammal-species unspecified); LD50: >5 gm/kg. Unreported (mammal-species unspecified); LD50: 500 mg/kg. Oral (rat); TDLo: 630 mg/kg/12W-C. Oral (rat); TDLo: 176 mg/kg. Oral (rat); TDLo: 176 mg/kg. Carcinogenic Effects:No data available Mutagenic Effects:No data available Tetratogenic Effects:Possible reproductive effector SECTION 12: Ecological Information Ecological Information:No information available SECTION 13: Disposal Considerations Disposal:Dispose of according to federal, state, and local regulations. SECTION 14: Transportation Shipping Name (CFR):Organotin compounds, solid, N.O.S. Hazard Class (CFR):6.1 Additional Hazard Class (CFR):NA Packaging Group (CFR):III UN ID Number (CFR):UN# 3146 Shipping Name (IATA):Organotin compound, solid, N.O.S. Hazard Class (IATA):6.1 Additional Hazard Class (IATA):NA Packaging Group (IATA):III UN ID Number (IATA):UN# 3146 SECTION 15: Regulatory Information TSCA:Not listed in the TSCA inventory. SARA (Title 313):Title compound not listed. Second Ingredient:none SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : WH5775000 CHEMICAL NAME : Stannane, acetoxytributyl- CAS REGISTRY NUMBER : 56-36-0 LAST UPDATED : 199712 DATA ITEMS CITED : 38 MOLECULAR FORMULA : C14-H30-O2-Sn MOLECULAR WEIGHT : 349.13 WISWESSER LINE NOTATION : 4-SN-4&4&OV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 99 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 56,240,1967 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 10,16,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 46 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 23,283,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01672 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes REFERENCE : BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 15,15,1958 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 10,16,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(9),50,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,301,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 630 mg/kg/12W-C TOXIC EFFECTS : Spinal Cord - other degenerative changes Related to Chronic Data - death REFERENCE : BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 15,15,1958 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 176 mg/kg SEX/DURATION : female 7-17 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 55,109,1991 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 176 mg/kg SEX/DURATION : female 7-17 day(s) after conception REFERENCE : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 55,109,1991 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Sn)/m3;STEL 0.2 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 4,61,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 0.1 mg(Sn)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,258,1971 OSHA PEL (Gen Indu):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Sn)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg(Sn)/m3;STEL 0.3 mg(Sn)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-HUNGARY:STEL 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Sn)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Sn)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.1 mg(Sn)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Sn)/m3;STEL 0.2 mg(Sn)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ORGANOTIN COMPOUND-air:10H TWA 0.1 mg(Sn)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0274 No. of Facilities: 76 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 685 (estimated)

安全

• 危害码 (欧洲): T,N
• 风险声明 (欧洲): 21-25-36/38-48/23/25-50/53
• 安全声明 (欧洲): S35-S36/37/39-S45-S60-S61
• 危险品运输编码: UN 3146 6.1/PG 2
• WGK德国: 3
• RTECS号: WH5775000
• 包装等级: III
• 危险类别: 6.1

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