161433-30-3

• 常用中文名：N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(4-(DIET
• 常用英文名：RH 414
• CAS号：161433-30-3
• 分子式：C₂₈H₄₃Br₂N₃
• 分子量：581.46900
• 发布时间：2018-12-30 11:47:52
• 更新时间：2024-02-18 11:10:34

• 化学试剂、有机中间体、精细化学品、药物研发

名称

• 中文名: N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(4-(DIET
• 英文名: Neurodye RH-414, pure
• 英文别名: PYRIDINIUM (4-[4-[4-(DIETHYLAMINO)PHENYL]-1,3-BUTADIENYL]-1-[3-(TRIETHYLAMMONIO)PROPYL]; NEURODYE RH-414; 3-[4-[(1E,3E)-4-[4-(diethylamino)phenyl]buta-1,3-dienyl]pyridin-1-ium-1-yl]propyl-triethylazanium,dibromide; N-(3-TRIETHYLAMMONIUMPROPYL)-4-(4-(4

物化性质

• 分子式: C₂₈H₄₃Br₂N₃
• 分子量: 581.46900
• 精确质量: 579.18200
• PSA: 7.12000
• 储存条件:

  保存方法：密闭，阴凉，干燥处

• 稳定性:

  避光

• 计算化学:

  1.疏水参数计算参考值（XlogP）:1.1

  2.氢键供体数量:3

  3.氢键受体数量:5

  4.可旋转化学键数量:5

  5.互变异构体数量:2

  6.拓扑分子极性表面积92.8

  7.重原子数量:22

  8.表面电荷:0

  9.复杂度:365

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：红色固体

  2. 密度（g/mL25 ºC,）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC0.6mmHg）：未确定

  7. 折射率：未确定

  8. 闪点（ºC0.6mmHg）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

生物活性

• 描述: RH 414是苯乙烯基吡啶染料。RH 414可用于突触囊泡膜运输的光学监测[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Bewick GS, et al. Illumination partly reverses the postsynaptic blockade of the frog neuromuscular junction by the styryl pyridinium dye RH414. Proc Biol Sci. 1994;258(1352):201-207.

MSDS

Name: Neurodye RH414 Material Safety Data Sheet Synonym: RH-414 CAS: 161433-30-3 Section 1 - Chemical Product MSDS Name:Neurodye RH414 Material Safety Data Sheet Synonym:RH-414 Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 161433-30-3 Neurodye RH414 unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Light sensitive. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 161433-30-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: red Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Moderately Soluble. Specific Gravity/Density: Molecular Formula: C32H49N3O4 Molecular Weight: 539.3607 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. Conditions to Avoid: Light. Incompatibilities with Other Materials: Not available. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 161433-30-3 unlisted. LD50/LC50: Not available. Carcinogenicity: Neurodye RH414 - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 161433-30-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 161433-30-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 161433-30-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 安全声明 (欧洲): S24/25