52722-86-8

• 常用中文名：4-羟基-1-(2-羟乙基)-2,2,6,6-四甲基哌啶
• 常用英文名：Hydroxyethyl tetramethylpiperidinol
• CAS号：52722-86-8
• 分子式：C₁₁H₂₃NO₂
• 分子量：201.30600
• 发布时间：2018-06-19 20:36:24
• 更新时间：2024-01-02 20:02:25
• 【用途一】
  用作受阻胺光稳定剂，也是合成受阻胺型光稳定剂的主要中间体
  【用途二】
  本品是受阻胺系列光稳定剂及有机合成的重要中间体。

名称

• 中文名: 1-(2'-羟乙基)-2,2,6,6-四甲基-4-哌啶醇
• 英文名: 1-(2-Hydroxyethyl)-2,2,6,6-Tetramethyl-4-Piperidinol
• 中文别名: 1-(2`-羟乙基)-2,2,6,6-四甲基-4-哌啶醇; 羟乙基四甲基哌啶醇; 4-羟基-1-(2-羟乙基)-2,2,6,6-四甲基哌啶; 光稳定剂HS-201
• 英文别名: 4-Hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol; EINECS 258-132-1; MFCD01321174; 1-(2-Hydroxyethyl)-2,2,6,6-tetramethylpiperidin-4-ol; Hydroxyethyl tetramethylpiperidinol; 1-(2’-Hydroxyethyl)-2,2,6,6-tetramethyl-4-piperidinol; 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine; 1-(2-Hydroxyethyl)-2,2,6,6-tetramethyl-4-piperidinol

物化性质

• 密度: 0.975 g/cm3
• 沸点: 302.6ºC at 760 mmHg
• 熔点: 180-184°C
• 分子式: C₁₁H₂₃NO₂
• 分子量: 201.30600
• 闪点: 130.2ºC
• 精确质量: 201.17300
• PSA: 43.70000
• LogP: 0.93050
• 外观性状: 白色晶体粉末
• 折射率: 1.471
• 储存条件:

  保持贮藏器密封、储存在阴凉、干燥的地方，确保工作间有良好的通风或排气装置

• 稳定性:

  如果遵照规格使用和储存则不会分解，未有已知危险反应

• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.7

  2.氢键供体数量:2

  3.氢键受体数量:3

  4.可旋转化学键数量:2

  5.互变异构体数量:无

  6.拓扑分子极性表面积43.7

  7.重原子数量:14

  8.表面电荷:0

  9.复杂度:184

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：未确定

  2. 密度（g/mL,25ºC）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）： 未确定

  4. 熔点（ºC）：180-184

  5. 沸点（ºC）：未确定

  6. 沸点（ºC，10mm hg）：未确定

  7. 折射率：未确定

  8. 闪点（°F）：未确定

  9. 比旋光度（ºC）：未确定

  10. 自燃点或引燃温度（ºC）： 未确定

  11. 蒸气压（kPa,20ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

MSDS

Section I.Chemical Product and Company Identification Chemical Name4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethyl piperidine Portland OR Synonym1-Piperidineethanol, 4-hydroxy-2,2,6,6-tetramethyl- (CA INDEX NAME); 1-(2-Hydroxyethyl)-2,2,6,6-tetramethyl-4-piperidinol; 4-Hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol Chemical FormulaC11H23NO CAS Number52722-86-8 Section II.Composition and Information on Ingredients Chemical NameCAS Number Percent (%)TLV/PELToxicology Data 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethyl52722-86-8 Min. 98.0 (GC) Not available.Not available. piperidine Section III. Hazards Identification No specific information is available in our data base regarding the toxic effects of this material for humans. However, Acute Health Effects exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. Chronic Health EffectsCARCINOGENIC EFFECTS : Not available. MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention. Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or Inhalation waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not improve. INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. Ingestion Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Section V.Fire and Explosion Data Not available. May be combustible at high temperature.Auto-Ignition Flammability Flash PointsFlammable LimitsNot available. Not available. These products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2). Combustion Products Fire HazardsNot available. Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards Risks of explosion of the product in presence of static discharge: Not available. Fire Fighting Media SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. and Instructions Consult with local fire authorities before attempting large scale fire-fighting operations. Continued on Next Page 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethyl piperidine Section VI.Accidental Release Measures Spill CleanupUse a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on Instructions disposal. Section VII. Handling and Storage Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool Handling and Storage place. Avoid excessive heat and light. Do not breathe dust. Information Always store away from incompatible compounds such as oxidizing agents. Section VIII. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Exposure LimitsNot available. Section IX. Physical and Chemical Properties Solid. (White Crystalline Powder)Solubility Physical state @ 20°CNot available. Not available. Specific Gravity Molecular Weight201.31Partition CoefficientNot available. Boiling PointNot available.Vapor PressureNot applicable. 186°C (366.8°F)Not available. Melting PointVapor Density Not available.VolatilityNot available. Refractive Index Not available. Critical TemperatureNot available.Odor ViscosityNot available.TasteNot available. Section X.Stability and Reactivity Data Stability This material is stable if stored under proper conditions. (See Section VII for instructions) Conditions of InstabilityAvoid excessive heat and light. Incompatibilities Reactive with oxidizing agents. Section XI. Toxicological Information RTECS NumberNot available. Eye Contact. Ingestion. Inhalation. Routes of Exposure Toxicity DataNot available. CARCINOGENIC EFFECTS : Not available. Chronic Toxic Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Acute Toxic EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However, exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. Section XII.Ecological Information Not available. Ecotoxicity Environmental FateNot available. Continued on Next Page 4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethyl piperidine Section XIII. Disposal Considerations Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a Waste Disposal combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section XIV. Transport Information DOT ClassificationNot a DOT controlled material (United States). Not applicable. PIN Number Proper Shipping NameNot applicable. Not applicable. Packing Group (PG) DOT Pictograms Section XV. Other Regulatory Information and Pictograms TSCA Chemical InventoryThis compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list. (EPA) WHMIS ClassificationNot controlled under WHMIS (Canada). On NDSL (Canada) EINECS Number (EEC) 258-132-1 EEC Risk StatementsNot available. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统，若无政府许可，勿将材料排入周围环境。

安全

• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 海关编码: 2933399090

合成路线

75-21-8 2403-88-5 ~% 52722-86-8

文献：Ciba-Geigy Corporation Patent: US4014887 A1, 1977 ;

上下游产品

上游产品  2
75-21-8 2403-88-5
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海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%