上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：2-异丙基-4-甲基-6-羟基嘧啶
纯度：98.0%
规格：
联系人：徐经理
联系电话：13311869306

上海吉至生化科技有限公司
上海市上海市奉贤区
产品名：2-异丙基-4-甲基-6-羟基嘧啶
纯度：98.0%
规格：25g/100g
联系人：刘佳
联系电话：18116092098

武汉吉鑫益邦生物科技有限公司
湖北省武汉市江汉区
产品名：2-异丙基-6-甲基-4-羟基嘧啶
纯度：99.0%
规格：500g/1kg/25kg/200kg
联系人：周美玲
联系电话：13260558730

盼得（上海）国际贸易有限公司
上海市上海市徐汇区
产品名：2-异丙基-6-甲基-4-羟基嘧啶
纯度：99.0%
规格：500g/1kg/25kg/200kg
联系人：叶经理
联系电话：18019361053

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2814-20-2生产厂家

2814-20-2价格

2814-20-2

2814-20-2结构式

常用中文名：2-异丙基-4-甲基-6-羟基嘧啶
常用英文名：pyrimidinol
CAS号：2814-20-2
分子式：C₈H₁₂N₂O
分子量：152.194
相关类别：化学农药原药杀虫剂中间体
发布时间：2019-02-17 17:30:20
更新时间：2024-01-02 10:23:32
【用途一】
用作医药中间体
【用途二】
2-异丙基-4-甲基-6-羟基嘧啶是杀虫剂二嗪磷的中间体。
【用途三】
有机磷农药二嗪磷、医药中间体。

化源商城直购

中文名	2-异丙基-6-甲基-4-嘧啶醇
英文名	6-methyl-2-propan-2-yl-1H-pyrimidin-4-one
中文别名	2-异丙基-4-甲基-6-羟基嘧啶安石榴苷 2-异丙基-6-甲基-4-吡啶醇
英文别名	2-Isopropyl-6-methyl-4-hydroxypyrimidine 2-Isopropyl-6-methylpyrimidin-4(3H)-one EINECS 220-561-7 6-hydroxy-2-isopropyl-4-methylpyrimidine 2-ISOPROPYL-6-METHYL-4-PYRIMIDONE 6-methyl-2-(propan-2-yl)pyrimidin-4(1H)-one 4-Pyrimidinol, 6-methyl-2-(1-methylethyl)- pyrimidinol 4(1H)-Pyrimidinone,6-methyl-2-(1-methylethyl) 4-hydroxy-2-isopropyl-6-methyl-pyrimidine IMHP 6-methyl-2-(propan-2-yl)pyrimidin-4-ol 6-methyl-2-(1-methylethyl)pyrimidin-4(1H)-one 6-Pyrimidinol,2-isopropyl-4-methyl 2-isopropyl-4-hydroxy-6-methylpyrimidine 2-Isopropyl-6-methyl-4(1H)-pyrimidinone 4(3H)-pyrimidinone, 6-methyl-2-(1-methylethyl)- 2-Isopropyl-6-methylpyrimidin-4(1H)-one 2-Isopropyl-6-methylpyrimidin-4-ol 2-Isopropyl-4-methyl-6-hydroxypyrimidine MFCD00044811 4(1H)-pyrimidinone, 6-methyl-2-(1-methylethyl)- 2-Isopropyl-6-methyl-4-pyrimidinol

密度	1.1±0.1 g/cm3
沸点	244.3±20.0 °C at 760 mmHg
熔点	172-175 °C(lit.)
分子式	C₈H₁₂N₂O
分子量	152.194
闪点	101.6±21.8 °C
精确质量	152.094955
PSA	46.01000
LogP	0.50
外观性状	固体;White to Light yellow powder to crystal
蒸汽压	0.0±0.5 mmHg at 25°C
折射率	1.528
储存条件	密封储存，储存于阴凉、干燥的库房。
稳定性	常温常压下稳定，避免与氧化剂接触。
计算化学	1.疏水参数计算参考值（XlogP）:0.7 2.氢键供体数量:1 3.氢键受体数量:1 4.可旋转化学键数量:1 5.互变异构体数量:9 6.拓扑分子极性表面积41.5 7.重原子数量:11 8.表面电荷:0 9.复杂度:239 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1. 性状：米色针状固体 2. 密度（g/mL,25℃）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：172-175 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC,5mmHg）：未确定 7. 折射率(n20/D)：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（mPa,20ºC）：未确定 12. 饱和蒸气压（kPa,25ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：不溶于水

Name:	2-Isopropyl-6-Methyl-4-Pyrimidinol 99% Material Safety Data Sheet
Synonym:	6-Methyl-2-(1-Methylethyl)-4(1H)-Pyrimidinone; 2-Isopropyl-4-Methyl-6-Oxypyrimidine; 2-Isopropyl-6-Methyl-3H-Pyrimidin-4-One
CAS:	2814-20-2

Section 1 - Chemical Product MSDS Name:2-Isopropyl-6-Methyl-4-Pyrimidinol 99% Material Safety Data Sheet
Synonym:6-Methyl-2-(1-Methylethyl)-4(1H)-Pyrimidinone; 2-Isopropyl-4-Methyl-6-Oxypyrimidine; 2-Isopropyl-6-Methyl-3H-Pyrimidin-4-One

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
2814-20-2	2-Isopropyl-6-Methyl-4-Pyrimidinol	99	220-561-7

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 2814-20-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Needles
Color: beige
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 172.00 - 174.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H12N2O
Molecular Weight: 152.20

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 2814-20-2: UW7525000 LD50/LC50:
CAS# 2814-20-2: Oral, mouse: LD50 = 2200 mg/kg; Oral, rat: LD50 = 2700 mg/kg.
Carcinogenicity:
2-Isopropyl-6-Methyl-4-Pyrimidinol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 2814-20-2: No information available.
Canada
CAS# 2814-20-2 is listed on Canada's NDSL List.
CAS# 2814-20-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2814-20-2 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

毒理学数据:

1、急性毒性：大鼠经口LD50：2700mg/kg；小鼠经口LD50：2200mg/kg；

2、其他多剂量毒性：大鼠经口TDLo：7800mg/kg/6W-I；

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UW7525000

CHEMICAL NAME :: 4(3H)-Pyrimidinone, 2-isopropyl-6-methyl-

CAS REGISTRY NUMBER :: 2814-20-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H12-N2-O

MOLECULAR WEIGHT :: 152.22

WISWESSER LINE NOTATION :: T6N CNJ BY1&1 DQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 18,208,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(3),69,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7800 mg/kg/6W-I

TOXIC EFFECTS :: Vascular - BP elevation not characterized in autonomic section Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(3),69,1987

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P261-P305 + P351 + P338
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	S26-S37/39
危险品运输编码	NONH for all modes of transport
WGK德国	2
RTECS号	UW7525000
海关编码	2933599090

上游产品 2
333-41-5 67-56-1
下游产品 5
333-41-5 2463-82-3 72799-31-6 87268-60-8
4595-69-1

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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