1066-30-4

• 常用中文名：醋酸铬
• 常用英文名：Chromium(III) acetate
• CAS号：1066-30-4
• 分子式：C₆H₉CrO₆
• 分子量：229.128
• 相关类别： 有机原料 有机金属盐
• 发布时间：2018-02-05 08:00:00
• 更新时间：2024-01-02 21:15:26
• Chromium(III) (acetate) (Chromic acetate) 是一种离子交联剂。

名称

• 中文名: 乙酸铬
• 英文名: Chromic acetate
• 中文别名: 醋酸铬
• 英文别名: chromium(lll) acetate; chromium(III) ethanoate; chromium(III) acetate; Chromic Acetate; EINECS 213-909-4; Chromium triacetate; chromium acetate; CHROME ACETATE; MFCD00036429; NA-9101; chromicacetate(iii); chromic triacetate; cromium acetate; acetic acid,chromium (III)-acetate; ChromicAcetatePure

物化性质

• 密度: 1.705
• 沸点: 212 °F at 760 mmHg
• 熔点: >400 °C
• 分子式: C₆H₉CrO₆
• 分子量: 229.128
• 精确质量: 228.980423
• PSA: 78.90000
• LogP: 0.04140
• 外观性状: 淡灰色绿色至带蓝色的绿色粉末
• 储存条件:

  密封干燥储存。

• 稳定性:

  易溶于水。本品实际是水合醋酸盐［Cr（H2O）6］（CH3COO）3。

• 水溶解性: slightly soluble
• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：228.980425 Da

  8、标称质量：229 Da

  9、平均质量：229.1282 Da

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:6

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积120

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:25.5

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:4

• 更多:

  1. 性状：为蓝紫色的针状结晶。

  2. 密度（g/cm³ ）：1.28

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,8mm）：未确定

  7. 折射率：未确定

  8. 闪点（ºF）：85

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：微溶于水，溶于热水，不溶于醇。

生物活性

• 描述: Chromium(III) (acetate) (Chromic acetate) 是一种离子交联剂。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Mahsa Baghban Salehi, et al. Rheological and transport properties of sulfonated polyacrylamide hydrogels for water shutoff in porous media. Polym. Adv. Technol. 2014, 25 396-405.

MSDS

Section 1: Product Identification Chemical Name:Chromium (III) acetate solution, 11.2-11.8% Cr CAS Registry Number:1066-30-4 Formula:Cr(OOCCH3)3 EINECS Number:none Chemical Family:metal acetate salt Synonym:Chromic acetate (III), Chromium triacetate, Acetic acid, chromium (III) salt Section 2: Composition and Information on Ingredients IngredientCAS NumberPercentACGIH (TWA)OSHA (PEL) Title Compound1066-30-450%0.5mg/m30.5mg/m3 water7732-18-550%no datano data Section 3: Hazards Identification Emergency Overview:Irritating to eyes and skin. May be harmful if swallowed. Possible risk of irreversible effects. Primary Routes of Exposure:Ingestion, eyes, inhalation Eye Contact:Causes slight to mild irritation of the eyes. Skin Contact:Causes slight to mild irritation of the skin. Inhalation:Material is an aqueous solution. Inhalation is not applicable. Mae harmful if swallowed. Ingestion may cause gastrointestinal distress, burning of throat, dizziness and Ingestion: weakness. Acute Health Affects:Irritating to skin, eyes and respiratory tract. May be harmful if swallowed. Chronic Health Affects:Possible risk of irreversible effects. NTP:Yes IARC:Yes OSHA:No SECTION 4: First Aid Measures Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need Eye Exposure: assistance in keeping their eye lids open. Get immediate medical attention. Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if Skin Exposure: irritation persists. Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty Inhalation: in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce Ingestion: vomiting only if directed by medical personnel. SECTION 5: Fire Fighting Measures Flash Point:none Autoignition Temperature:none Explosion Limits:none Extinguishing Medium:carbon dioxide, dry powder or foam If involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained Special Fire Fighting Procedures: breathing apparatus and full protective clothing. Hazardous Combustion andIf involved in a fire this material may emit toxic organic fumes. Decomposion Products: Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards. SECTION 6: Accidental Release Measures Spill and Leak Procedures:Small spills can be absorbed in vermiculite or other suitable adsorbent. SECTION 7: Handling and Storage Handling and Storage:Store in a tightly sealed container. SECTION 8: Exposure Controls and Personal Protection Eye Protection:Always wear approved safety glasses when handling a chemical substance in the laboratory. Skin Protection:Wear protective clothing and gloves. Ventilation:If possible, handle the material in an efficient fume hood. Respirator:No respirator required. Ventilation:If possible, handle the material in an efficient fume hood. Additional Protection:No additional protection required. SECTION 9: Physical and Chemical Properties Color and Form:liq. Molecular Weight:229.13 Melting Point:no data Boiling Point:no data Vapor Pressure:no data Specific Gravity:1.28 Odor:none Solubility in Water:material is an aqueous sol. SECTION 10: Stability and Reactivity Stability:air and moisture stable liquid Hazardous Polymerization:no hazardous polymerization Conditions to Avoid:none Incompatibility:none Decomposition Products:Carbon dioxide, carbon monoxide, organic vapors, and metal oxides SECTION 11: Toxicological Information Intravenous (mouse); LDLo: 2290 mg/kg. Intravenous (rabbit); LDLo:1604 mg/kg. Intravenous (frog); LDLo: 6185 mg/kg. Implant (rat); TDLo: 1000 mg/kg/56W-I. Bacteria-Escherichia coli; Mutation in microorganisms: 16 RTECS Data:mmol/L. Bacteria-Escheichia coli; DNA repair: 93 ug/well. Bacteria-Bacillus subtilis; DNA repair: 160 mmol/L. Human Leukocyte; Cytogenetic analysis: 16 umol/L. Hamster Ovary; Cytogenetic analysis: 150 mg/L. Hamster Ovary; Mutation in mammalian somatic cells: 200 umol/L. Carcinogenic Effects:No data available Mutagenic Effects:Possible mutagen Tetratogenic Effects:No data available SECTION 12: Ecological Information Ecological Information:No information available SECTION 13: Disposal Considerations Disposal:Dispose of according to local, state and federal regulations. SECTION 14: Transportation Shipping Name (CFR):Non-hazardous Hazard Class (CFR):NA Additional Hazard Class (CFR):NA Packaging Group (CFR):NA UN ID Number (CFR):NA Shipping Name (IATA):Non-hazardous Hazard Class (IATA):NA Additional Hazard Class (IATA):NA Packaging Group (IATA):NA UN ID Number (IATA):NA SECTION 15: Regulatory Information TSCA:Listed in the TSCA inventory SARA (Title 313):Title compound see Category Code N090 for reporting. Second Ingredient:none SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 1、急性毒性：兔子静脉注射LDLo：1604mg/kg 小鼠静脉注射LCLo：2290mg/kg 2、 致肿瘤性：大鼠注入TDLO：1000mg/kg/56W-I CHEMICAL IDENTIFICATION RTECS NUMBER : AG2975000 CHEMICAL NAME : Acetic acid, chromium(3+) salt CAS REGISTRY NUMBER : 1066-30-4 LAST UPDATED : 199712 DATA ITEMS CITED : 27 MOLECULAR FORMULA : C6-H9-O6.Cr MOLECULAR WEIGHT : 229.15 WISWESSER LINE NOTATION : OV1 3 &-CR- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2290 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1604 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 6185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1000 mg/kg/56W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application MUTATION DATA TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 200 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 117,279,1983 *** REVIEWS *** ACGIH TLV-TWA 0.5 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,165,1987 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 23,205,1980 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 49,49,1990 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Cr,22,1974 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Cr)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,35,1971 OSHA PEL (Gen Indu):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg(Cr)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84289 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 168 (estimated)

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 危险品运输编码: UN 9101

合成路线

7738-94-5 64-19-7 ~% 1066-30-4

文献：EP2039673 A1, ; Page/Page column 12 ;

108-24-7 ~% 1066-30-4

文献：Journal of the American Chemical Society, vol. 33, p. 702

5990-10-3 ~% 1066-30-4

文献：Journal of Catalysis, , vol. 105, p. 249 - 253

14977-61-8 64-19-7 ~% 1066-30-4

文献：Journal fuer Praktische Chemie (Leipzig), , vol. 4, p. 211 - 226 Cr: MVol.B, 133, page 274 - 275

53668-83-0 ~% 1066-30-4

文献：Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), , p. 734 - 740

546-67-8 ~% 1066-30-4

文献：Monatshefte fuer Chemie, vol. 3, p. 252

上下游产品

上游产品  6
7738-94-5 64-19-7 108-24-7 14977-61-8
53668-83-0 546-67-8
下游产品  10
76-84-6 93-55-0 454-14-8 947-84-2
945-51-7 611-94-9 84-54-8 90-96-0
611-97-2 35845-67-1

制备

1.往六水合三氯化铬［Cr（H2O）6Cl3］的稀水溶液中加入稀氨水，煮沸而生成氢氧化铬（需要新鲜制备、并经充分水洗而不含氯离子的）。往其中加入过量的乙酸。反应进行时放出大量的热。数小时后析出结晶，可从母液中分离出结晶，并用丙酮和乙醚充分洗涤，置于硫酸干燥器中干燥。

2. 将氢氧化铬溶于乙酸中反应而得：