17575-21-2

• 常用中文名：毛花洋地黄苷B
• 常用英文名：Lanatoside B
• CAS号：17575-21-2
• 分子式：C₄₉H₇₆O₂₀
• 分子量：985.12
• 相关类别： 研究领域 心血管疾病
• 发布时间：2018-07-13 17:07:12
• 更新时间：2024-01-10 18:51:32
• Lanatoside B是一种可以从洋地黄叶片中分离出来的卡酚内酯[1]。

名称

• 中文名: 毛花洋地黄苷B
• 英文名: lanatoside b
• 中文别名: 毛花洋地黄苷 b
• 英文别名: Lanatosid-B; LANTOSIDEB; digilanidb; Digilanide B

物化性质

• 密度: 1.42g/cm3
• 熔点: 245-248ºC
• 分子式: C₄₉H₇₆O₂₀
• 分子量: 985.12
• 精确质量: 984.49300
• PSA: 288.28000
• LogP: 0.61310
• 折射率: 1.608

生物活性

• 描述: Lanatoside B是一种可以从洋地黄叶片中分离出来的卡酚内酯[1]。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Fernão Castro Braga, et al. Variation of cardenolides with growth in a Digitalis lanata Brazilian cultivar. Phytochemistry, 45 (3), 1997, 473-476.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OE2040000 CHEMICAL NAME : Lanatoside B CAS REGISTRY NUMBER : 17575-21-2 BEILSTEIN REFERENCE NO. : 0078394 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C49-H76-O20 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 12 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 177,60,1934 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 388 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,236,1942 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 3695 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 252,314,1966 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,52,1963