121-29-9

• 常用中文名：除虫菊素
• 常用英文名：pyrethrin 2
• CAS号：121-29-9
• 分子式：C₂₂H₂₈O₅
• 分子量：372.455
• 相关类别： 化学农药原药 杀虫剂 拟除虫菊脂杀虫剂
• 发布时间：2018-02-05 08:00:00
• 更新时间：2024-01-01 20:01:11

• 1.可用于生产气雾杀虫剂、蚊香、动物香波及绿色农药等

  2.除虫菊素作用于细胞膜上的钠离子通道，对突触体上ATP酶的活性也有影响。增效醚等增效剂对除虫菊素有明显的增效作用。

名称

• 中文名: 除虫菊素Ⅱ
• 英文名: pyrethrin II
• 中文别名: 除虫菊素
• 英文别名: (1S)-2-methyl-4-oxo-3-(2Z)-2,4-pentadien-1-yl-2-cyclopenten-1-yl (1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxo-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate; (1R,3R)-3-[(1E)-3-Méthoxy-2-méthyl-3-oxo-1-propèn-1-yl]-2,2-diméthylcyclopropanecarboxylate de (1S)-2-méthyl-4-oxo-3-[(2E)-2,4-pentadièn-1-yl]-2-cyclopentén-1-yle; (1S)-2-Methyl-4-oxo-3-[(2E)-penta-2,4-dien-1-yl]cyclopent-2-en-1-yl-(1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxoprop-1-en-1-yl]-2,2-dimethylcyclopropancarboxylat; Cyclopropanecarboxylic acid, 3-[(1E)-3-methoxy-2-methyl-3-oxo-1-propen-1-yl]-2,2-dimethyl-, (1S)-2-methyl-4-oxo-3-[(2E)-2,4-pentadien-1-yl]-2-cyclopenten-1-yl ester, (1R,3R)-; (1S)-2-Methyl-4-oxo-3-[(2E)-2,4-pentadien-1-yl]-2-cyclopenten-1-yl (1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxo-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate; (Z)-(S)-2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl (E)-(1R,3R)-3-(2-methoxycarbonylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; PYRETHRIN 2; (1S)-2-Methyl-4-oxo-3-[(2E)-penta-2,4-dien-1-yl]cyclopent-2-en-1-yl (1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxoprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate; (1S)-2-methyl-4-oxo-3-[(2Z)-penta-2,4-dien-1-yl]cyclopent-2-en-1-yl (1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxoprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate; Pyrethrin II; (Z)-(S)-2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl (E)-(1R)-trans-3-(2-methoxycarbonylprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate; (Z)-(S)-2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl pyrethrate; (1S)-2-Methyl-4-oxo-3-[(2E)-2,4-pentadien-1-yl]-2-cyclopenten-1-yl-(1R,3R)-3-[(1E)-3-methoxy-2-methyl-3-oxo-1-propen-1-yl]-2,2-dimethylcyclopropancarboxylat; EINECS 204-462-6

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 473.7±45.0 °C at 760 mmHg
• 分子式: C₂₂H₂₈O₅
• 分子量: 372.455
• 闪点: 203.8±28.8 °C
• 精确质量: 372.193665
• PSA: 69.67000
• LogP: 4.43
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.528
• 储存条件:

  密封保存。

• 稳定性:

  1.对光、热、酸、碱均不稳定，易分解，在空气中也不稳定，加入抗氧化剂可缓解其氧化作用。

• 分子结构:

  1、 摩尔折射率：102.41

  2、 摩尔体积（cm³/mol）：332.3

  3、 等张比容（90.2K）：839.4

  4、 表面张力（dyne/cm）：40.7

  5、 介电常数（F/m）：

  6、 偶极距（D）：

  7、 极化率（10^-24cm³）：40.59

• 更多:

  1.性状：浅黄色油状粘稠物。

  2.溶解性：不溶于水，易溶于有机溶剂。

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GZ0700000 CHEMICAL NAME : Cyclopropaneacrylic acid, 3-carboxy-alpha,2,2-trimethyl-, 1-methyl ester, ester with 4- hydroxy-3-methyl-2-(2,4-pentadienyl)-2-cyclopenten-1- one CAS REGISTRY NUMBER : 121-29-9 LAST UPDATED : 199701 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C22-H28-O5 MOLECULAR WEIGHT : 372.50 WISWESSER LINE NOTATION : L5V BUTJ B2U2U1 C1 DOV- BL3TJ A1 A1 C1UY1&VO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - man DOSE/DURATION : 1029 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,17,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : PCBPBS Pesticide Biochemistry and Physiology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1971- Volume(issue)/page/year: 2,308,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 37,2681,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83467 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 17 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83467 No. of Facilities: 241 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 5966 (estimated) No. of Female Employees: 390 (estimated)

安全

• 危害码 (欧洲): Xn: Harmful;N: Dangerous for the environment;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S13;S60;S61
• 危险品运输编码: UN 2902
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 29183000

制备

1.存在于菊科 （Compositae）菊属（Chrysanthemum）除虫菊亚属 （Pyrethrum）的若干种植物的花中，尤以白花除 虫 菊 （Pyrethrum cinerariaefolium）中的有效成分含量最高。除虫菊干花中含除虫菊素一般为0.9%～1.3%，经石油醚回流萃取，浓缩，得粗制黏稠物约含除虫菊素30%，经过脱蜡和脱色，得含除虫菊素60%的精品，可供配制浸膏和加工其他制剂之用，如再用硝基甲烷等作进一步精制，最后可获得除虫菊素含量达80%～85%的近于无色黏稠油状高纯度产品。也可以用混合溶剂抽提，如甲醇／煤油、石油醚／乙腈、石油醚／硝基甲烷等。