81552-33-2

• 常用中文名：刀豆素B
• 常用英文名：Concanamycin B
• CAS号：81552-33-2
• 分子式：C₄₅H₇₃NO₁₄
• 分子量：852.059
• 发布时间：2018-07-06 18:07:10
• 更新时间：2024-01-10 18:08:57
• Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases

名称

• 中文名: 刀豆素B
• 英文名: concanamycin b
• 英文别名: 8-Deethyl-8-methylconcanamycin A; ConcanaMycin B (high purity); L-glycero-Pentopyranose, 3-O-[4-O-(aminocarbonyl)-2,6-dideoxyhexopyranosyl]-2,4-dideoxy-1-C-[(3S)-3-[(4E,6E,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxooxacycloo ;ctadeca-4,6,14,16-tetraen-2-yl]-2-hydroxy-1-methylbutyl]-4-methyl-5-C-[(1E)-1-propen-1-yl]-, (4ξ)-; (4ξ)-3-O-(4-O-Carbamoyl-2,6-dideoxyhexopyranosyl)-2,4-dideoxy-1-C-{(4S)-4-[(4E,6E,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen -2-yl]-3-hydroxy-2-pentanyl}-4-methyl-5-[(1E)-1-propen-1-yl]-L-glycero-pentopyranose

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 960.2±65.0 °C at 760 mmHg
• 分子式: C₄₅H₇₃NO₁₄
• 分子量: 852.059
• 闪点: 534.5±34.3 °C
• 精确质量: 851.503113
• PSA: 225.92000
• LogP: 3.34
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.556
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GK6889000 CHEMICAL NAME : Concanamycin A, 8-deethyl-8-methyl- CAS REGISTRY NUMBER : 81552-33-2 LAST UPDATED : 199303 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C45-H73-N-O14 MOLECULAR WEIGHT : 852.19 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,1333,1984