77-66-7

• 常用中文名：乙酰溴米那
• 常用英文名：acetyl carbromal
• CAS号：77-66-7
• 分子式：C₉H₁₅BrN₂O₃
• 分子量：279.13100
• 相关类别： 有机原料 烃类化合物及其衍生物 烃类磺化物
• 发布时间：2018-05-03 08:00:00
• 更新时间：2024-02-04 11:23:12

名称

• 中文名: 乙酰溴米那
• 英文名: N-(acetylcarbamoyl)-2-bromo-2-ethylbutanamide
• 中文别名: 阿巴辛; N-乙醯-N-溴二乙基乙醯脲
• 英文别名: Paxarel; Acecarbromal; Acetcarbromal; Darolon; Acetylcarbromal; Carbased; Acetyladalin; Abasin; Ibatran; Acetcarbromalum; N-Acetyl-N'-bromdiaethylacetyl-harnstoff; Acetkarbromal

物化性质

• 密度: 1.4g/cm3
• 熔点: 108-109°
• 分子式: C₉H₁₅BrN₂O₃
• 分子量: 279.13100
• 精确质量: 278.02700
• PSA: 75.27000
• LogP: 2.09420
• 折射率: 1.5
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YR6475000 CHEMICAL NAME : Urea, 1-acetyl-3-(2-bromo-2-ethylbutyryl)- CAS REGISTRY NUMBER : 77-66-7 BEILSTEIN REFERENCE NO. : 1791982 LAST UPDATED : 199710 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C9-H15-Br-N2-O3 MOLECULAR WEIGHT : 279.17 WISWESSER LINE NOTATION : EX2&2&VMVMV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 7 mg/kg TOXIC EFFECTS : Behavioral - toxic psychosis REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,423,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada) *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80394 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated)

合成路线

77-65-6 108-24-7 ~% 77-66-7

文献：Bayer and Co. Patent: DE327129 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 809

3998-25-2 ~% 77-66-7

文献：Bayer and Co. Patent: DE286760 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 704