17570-98-8

• 常用中文名：2-溴-1-(2-吡啶基)-1-乙酮 氢溴酸
• 常用英文名：2-Bromo-1-pyridin-2-ylethanone hydrobromide
• CAS号：17570-98-8
• 分子式：C₇H₇Br₂NO
• 分子量：280.945
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 吡啶衍生物
• 发布时间：2018-06-21 18:11:19
• 更新时间：2024-01-02 17:14:42
• 下载msds

名称

• 中文名: 2-溴-1-(2-吡啶基)-1-乙酮氢溴酸
• 英文名: 2-(Bromoacetyl)Pyridine Hydrobromide
• 中文别名: 2-溴乙酰基吡啶氢溴酸盐
• 英文别名: 2-(Bromoacetyl)pyridine hydrobromide; Ethanone, 2-bromo-1-(2-pyridinyl)-, hydrobromide (1:1); 2-Bromo-1-(2-pyridinyl)ethanone hydrobromide (1:1); Ethanone, 2-bromo-1-(2-pyridinyl)-, hydrobromide; 2-Bromo-1-pyridin-2-ylethanone hydrobromide; MFCD02181196; 2-Bromo-1-(pyridin-2-yl)ethanone hydrobromide (1:1); 2-bromo-1-pyridin-2-ylethanone,hydrobromide; 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide; T6NJ BV1E &&HBr

物化性质

• 密度: 1.57g/cm3
• 沸点: 249.1ºC at 760mmHg
• 熔点: 205ºC
• 分子式: C₇H₇Br₂NO
• 分子量: 280.945
• 闪点: 104.5ºC
• 精确质量: 278.889435
• PSA: 29.96000
• LogP: 2.61730
• 蒸汽压: 0.0233mmHg at 25°C
• 储存条件: 室温

MSDS

Name: 2-Bromo-1-(2-pyridinyl)-1-ethanone hydrobromide 97% Material Safety Data Sheet Synonym: CAS: 17570-98-8 Section 1 - Chemical Product MSDS Name:2-Bromo-1-(2-pyridinyl)-1-ethanone hydrobromide 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 17570-98-8 2-Bromo-1-(2-pyridinyl)-1-ethanone hy 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a tightly closed container. Store in a dry area. Keep refrigerated. (Store below 4C/39F.) Store under an inert atmosphere. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 17570-98-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystals Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H7Br2NO Molecular Weight: 280.95 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 17570-98-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Bromo-1-(2-pyridinyl)-1-ethanone hydrobromide - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 17570-98-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 17570-98-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 17570-98-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2933399090

合成路线

1122-62-9 ~97% 17570-98-8

文献：PFIZER PRODUCTS INC. Patent: WO2008/4117 A1, 2008 ; Location in patent: Page/Page column 85 ;

1122-54-9 ~90% 17570-98-8

文献：Pharmacia Italia S.p.A. Patent: US2007/142414 A1, 2007 ; Location in patent: Page/Page column 18 ; US 20070142414 A1

113738-31-1 ~19% 17570-98-8

文献：Ruano, J. L. Garcia; Pedregal, C.; Rodriguez, J. H. Tetrahedron, 1987 , vol. 43, # 19 p. 4407 - 4416

上下游产品

上游产品  3
1122-62-9 1122-54-9 113738-31-1
下游产品  4
27302-93-8 845714-00-3 30235-26-8 27302-90-5

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%