56469-01-3

• 常用中文名：1,2-Propanediol, 3-(8-quinolyloxy)-
• 常用英文名：1,2-Propanediol, 3-(8-quinolyloxy)-
• CAS号：56469-01-3
• 分子式：C₁₂H₁₃NO₃
• 分子量：219.23700
• 发布时间：2016-06-06 16:18:36
• 更新时间：2024-01-28 20:41:17

名称

• 英文名: 3-quinolin-8-yloxypropane-1,2-diol

物化性质

• 密度: 1.295g/cm3
• 沸点: 452.8ºC at 760 mmHg
• 分子式: C₁₂H₁₃NO₃
• 分子量: 219.23700
• 闪点: 227.6ºC
• 精确质量: 219.09000
• PSA: 62.58000
• LogP: 0.96680
• 折射率: 1.642

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TZ1143000 CHEMICAL NAME : 1,2-Propanediol, 3-(8-quinolyloxy)- CAS REGISTRY NUMBER : 56469-01-3 BEILSTEIN REFERENCE NO. : 0178787 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H13-N-O3 MOLECULAR WEIGHT : 219.26 WISWESSER LINE NOTATION : T66 BNJ JO1YQ1Q HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 548 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,470,1948

合成路线

148-24-3 96-24-2 ~39% 56469-01-3

文献：Dishong, Dennis M.; Diamond, Craig J.; Cinoman, Michael I.; Gokel, Geoge W. Journal of the American Chemical Society, 1983 , vol. 105, # 3 p. 586 - 593

148-24-3 106-89-8 ~% 56469-01-3

文献：Otsuka Pharmaceutical Co., Ltd. Patent: US4065456 A1, 1977 ; US 4065456 A

96-24-2 ~% 56469-01-3

文献：Fuentes An. Fac. Farm Bioquim. Univ. San Marcos, 1952 , vol. 3, p. 501,506

上下游产品

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148-24-3 96-24-2 106-89-8
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