7492-32-2

• 常用中文名：Isopropamide
• 常用英文名：Isopropamide
• CAS号：7492-32-2
• 分子式：C₂₃H₃₃N₂O+
• 分子量：353.52100
• 发布时间：2016-11-17 14:36:43
• 更新时间：2024-01-18 11:27:26
• Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt.

名称

• 英文名: (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium
• 英文别名: (3-Aminocarbonyl-3,3-diphenylpropyl)diisopropylmethylaminium

物化性质

• 分子式: C₂₃H₃₃N₂O+
• 分子量: 353.52100
• 精确质量: 353.25900
• PSA: 43.09000
• LogP: 4.81180

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BP0690000 CHEMICAL NAME : Ammonium, (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl- CAS REGISTRY NUMBER : 7492-32-2 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C23-H33-N2-O MOLECULAR WEIGHT : 353.58 WISWESSER LINE NOTATION : ZVXR&R&2K1&Y1&1&Y1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1032 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,132,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 957 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,132,1970