5581-40-8

• 常用中文名：二甲法登
• 常用英文名：Dimefadane
• CAS号：5581-40-8
• 分子式：C₁₇H₁₉N
• 分子量：237.33900
• 发布时间：2018-09-08 17:47:07
• 更新时间：2024-01-14 06:24:40

名称

• 中文名: 二甲法登
• 英文名: N,N-dimethyl-3-phenyl-2,3-dihydro-1H-inden-1-amine
• 英文别名: Dimefadano [INN-Spanish]; N,N-Dimethyl-3-phenyl-1-indanamine; SKF 1340; 1H-Inden-1-amine,2,3-dihydro-N,N-dimethyl-3-phenyl; Dimefadanum [INN-Latin]; dimethyl-(3-phenyl-indan-1-yl)-amine; clothiapine; Dimethyl fandane; DIMEFADANE; Dimefadane [USAN:INN]; F 1340; 1-Indanamine,N,N-dimethyl-3-phenyl; Dimethyl-(3-phenyl-indan-1-yl)-amin

物化性质

• 密度: 1.07g/cm3
• 沸点: 349.7ºC at 760 mmHg
• 分子式: C₁₇H₁₉N
• 分子量: 237.33900
• 闪点: 149.5ºC
• 精确质量: 237.15200
• PSA: 3.24000
• LogP: 3.82490
• 折射率: 1.608

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NK4025000 CHEMICAL NAME : 1-Indanamine, N,N-dimethyl-3-phenyl- CAS REGISTRY NUMBER : 5581-40-8 BEILSTEIN REFERENCE NO. : 3322336 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H19-N MOLECULAR WEIGHT : 237.37 WISWESSER LINE NOTATION : L56T&J BN1&1 DR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 176 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - wild bird species DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

合成路线

30516-40-6 ~% 5581-40-8

文献：Barltrop et al. Journal of the Chemical Society, 1956 , p. 2928,2936

16618-72-7 ~% 5581-40-8

文献：Barltrop et al. Journal of the Chemical Society, 1956 , p. 2928,2936

50-00-0 108716-04-7 ~% 5581-40-8

文献：Barltrop et al. Journal of the Chemical Society, 1956 , p. 2928,2936

16618-72-7 124-40-3 ~% 5581-40-8

文献：Schering A.G. Patent: DE951628 , 1953 ;

106783-39-5 124-40-3 ~% 5581-40-8

文献：Schering A.G. Patent: DE946058 , 1953 ;

上下游产品

上游产品  6
30516-40-6 16618-72-7 50-00-0 108716-04-7
124-40-3 106783-39-5
下游产品  0