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110311-27-8

110311-27-8结构式

常用中文名：磺氯苯脲
常用英文名：Sulofenur
CAS号：110311-27-8
分子式：C₁₆H₁₅ClN₂O₃S
分子量：350.82000
发布时间：2018-03-27 08:00:00
更新时间：2024-01-03 18:47:06

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中文名	磺氯苯脲
英文名	1-(4-chlorophenyl)-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)urea
英文别名	N-(5-Indansulfonyl)-N'-(4-chlorophenyl)urea SULOFENUR Sulofenurum [INN-Latin] N-[[(4-chlorophenyl)amino]carbonyl]-indan-5-sulfonamide N-(Indanyl-5-sulfonyl)-N'-(4-chlorophenyl)urea N-([(4-chlorophenyl)amino]carbonyl)-2,3-dihydro-1H-indene-5-sulfonamide 1-(p-Chlorophenyl)-3-(5-indanylsulfonyl)urea

密度	1.449g/cm3
分子式	C₁₆H₁₅ClN₂O₃S
分子量	350.82000
精确质量	350.04900
PSA	83.65000
LogP	4.88380
折射率	1.656

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK8730000

CHEMICAL NAME :: 1H-Indene-5-sulfonamide, 2,3-dihydro-N-(((4-chlorophenyl)amino)carbonyl)-

CAS REGISTRY NUMBER :: 110311-27-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H15-Cl-N2-O3-S

MOLECULAR WEIGHT :: 350.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 16,517,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 16,517,1991 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2940 mg/kg

SEX/DURATION :: male 14 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 6,47,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2940 mg/kg

SEX/DURATION :: male 14 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987- Volume(issue)/page/year: 6,47,1992

海关编码	2935009090

35203-93-1结构式

35203-93-1

104-12-1结构式

104-12-1

~76%

110311-27-8结构式

110311-27-8

文献：Howbert; Grossman; Crowell; Rieder; Harper; Kramer; Tao; Aikins; Poore; Rinzel; Grindey; Shaw; Todd Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2393 - 2407

52405-96-6结构式

52405-96-6

106-47-8结构式

106-47-8

~86%

110311-27-8结构式

110311-27-8

文献：Howbert; Grossman; Crowell; Rieder; Harper; Kramer; Tao; Aikins; Poore; Rinzel; Grindey; Shaw; Todd Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2393 - 2407

52205-86-4结构式

52205-86-4

106-47-8结构式

106-47-8

~%

110311-27-8结构式

110311-27-8

文献：Eli Lilly and Company Patent: US5116874 A1, 1992 ;

上游产品 4
35203-93-1 104-12-1 52405-96-6 106-47-8
下游产品 0

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%