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3781-28-0

3781-28-0结构式
3781-28-0结构式
  • 常用中文名:普罗哌隆
  • 常用英文名:Propyperone
  • CAS号:3781-28-0
  • 分子式:C23H33FN2O2
  • 分子量:388.51900
  • 发布时间:2018-08-09 14:16:33
  • 更新时间:2024-01-09 18:56:46

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中文名 普罗哌隆
英文名 1-(4-fluorophenyl)-4-(4-piperidin-1-yl-4-propanoylpiperidin-1-yl)butan-1-one
英文别名 R 4082
Floropipeton
Propiperona [INN-Spanish]
1-<3-(4-Fluor-benzoyl)-propyl>-4-piperidino-4-propionyl-piperidin
Propyperonum [INN-Latin]
Propyperone
4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone
BUTYROPHENONE,4'-FLUORO-4-(4-PIPERIDINO-4-PROPIONYLPIPERIDINO)
1-(4-fluoro-phenyl)-4-(4'-propionyl-octahydro-[1,4']bipyridinyl-1'-yl)-butan-1-one
Propiperona
密度 1.112g/cm3
沸点 515.6ºC at 760mmHg
分子式 C23H33FN2O2
分子量 388.51900
闪点 265.7ºC
精确质量 388.25300
PSA 40.62000
LogP 3.96400
折射率 1.534

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EU4375000
CHEMICAL NAME :
Butyrophenone, 4'-fluoro-4-(4-piperidino-4-propionylpiperidino)-
CAS REGISTRY NUMBER :
3781-28-0
BEILSTEIN REFERENCE NO. :
0495940
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C23-H33-F-N2-O2
MOLECULAR WEIGHT :
388.58
WISWESSER LINE NOTATION :
T6NTJ A- DT6NTJ A3VR DF& DV2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,192,1972

海关编码 2933399090
海关编码 2933399090
中文概述 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%