467-22-1

• 常用中文名：CARBIPHENE HYDROCHLORIDE
• 常用英文名：CARBIPHENE HYDROCHLORIDE
• CAS号：467-22-1
• 分子式：C₂₈H₃₅ClN₂O₂
• 分子量：467.04300
• 发布时间：2017-01-07 02:54:41
• 更新时间：2024-01-07 11:23:52

名称

• 英文名: 2-ethoxy-N-methyl-N-[2-[methyl(2-phenylethyl)amino]ethyl]-2,2-diphenylacetamide,hydrochloride
• 英文别名: Etymide hydrochloride; Etomide hydrochloride; Bandol; Carbiphene hydrochloride; Carbiphene HCl; Jubalon; Carbifene hydrochloride; Carbifene

物化性质

• 沸点: 566.3ºC at 760 mmHg
• 分子式: C₂₈H₃₅ClN₂O₂
• 分子量: 467.04300
• 闪点: 296.3ºC
• 精确质量: 466.23900
• PSA: 32.78000
• LogP: 5.40160
• 蒸汽压: 7.67E-13mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB8400000 CHEMICAL NAME : Acetamide, 2-ethoxy-N-methyl-N-(2-(methylphenethylamino)ethyl)-2 ,2-diphenyl-, hydrochloride CAS REGISTRY NUMBER : 467-22-1 LAST UPDATED : 199007 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C28-H34-N2-O2.Cl-H MOLECULAR WEIGHT : 467.10 WISWESSER LINE NOTATION : 2OXR&R&VN1&2M2R D1 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 2 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,547,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 370 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 190 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965