CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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AB8400000
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CHEMICAL NAME :
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Acetamide, 2-ethoxy-N-methyl-N-(2-(methylphenethylamino)ethyl)-2 ,2-diphenyl-, hydrochloride
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CAS REGISTRY NUMBER :
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467-22-1
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LAST UPDATED :
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199007
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C28-H34-N2-O2.Cl-H
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MOLECULAR WEIGHT :
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467.10
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WISWESSER LINE NOTATION :
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2OXR&R&VN1&2M2R D1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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2 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,547,1963
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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370 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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190 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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40 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
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