26078-25-1

• 常用中文名：7-(乙氨基)-4,6-二甲基香豆素
• 常用英文名：Coumarin 2
• CAS号：26078-25-1
• 分子式：C₁₃H₁₅NO₂
• 分子量：217.26400
• 相关类别： 化学试剂 有机试剂 芳香酮
• 发布时间：2018-04-12 08:00:00
• 更新时间：2024-01-03 08:01:57
• 4,6-二甲基-7-乙基氨基香豆素是一种用于脉冲和连续操作的激光染料[1]。

名称

• 中文名: 香豆素 2
• 英文名: 7-(ethylamino)-4,6-dimethylchromen-2-one
• 中文别名: 4,6-二甲基-7-乙基氨基香豆素; 香豆素450; 香豆素2; 7-(乙氨基)-4,6-二甲基香豆素; 7-(乙氨基)-4,6-二甲基-2H-1-苯并吡喃-2-酮
• 英文别名: MFCD00006860; 7-(Ethylamino)-4,6-dimethylcoumarin; 7-(Ethylamino)-4,6-dimethyl-2H-chromen-2-one; Coumarin 450; Coumarin 2,laser grade; EINECS 247-446-4; 2H-1-Benzopyran-2-one,7-(ethylamino)-4,6-dimethyl; 4,6-Dimethyl-7-(ethylamino)coumarin; Coumarin 2; 7-Ethylamino-4,6-dimethyl coumarin

物化性质

• 密度: 1.159g/cm3
• 沸点: 384.4ºC at 760mmHg
• 熔点: 168-170 °C
• 分子式: C₁₃H₁₅NO₂
• 分子量: 217.26400
• 闪点: 186.3ºC
• 精确质量: 217.11000
• PSA: 42.24000
• LogP: 2.91460
• 外观性状: 淡黄色结晶粉末
• 蒸汽压: 4.1E-06mmHg at 25°C
• 折射率: 1.593
• 储存条件:

  密闭于阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 水溶解性: 略溶于水
• 分子结构:

  1、 摩尔折射率：62.24

  2、 摩尔体积（m³/mol）：196.0

  3、 等张比容（90.2K）：489.6

  4、 表面张力（dyne/cm）：38.9

  5、 极化率（10 ^-24cm ³）：24.67

• 计算化学:

  1.疏水参数计算参考值（XlogP）:2.5

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:2

  5.互变异构体数量:7

  6.拓扑分子极性表面积38.3

  7.重原子数量:16

  8.表面电荷:0

  9.复杂度:311

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：168-170

  5. 沸点（ºC,常压）：无可用

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：无可用

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：略溶于水

生物活性

• 描述: 4,6-二甲基-7-乙基氨基香豆素是一种用于脉冲和连续操作的激光染料[1]。
• 相关类别:
  研究领域 >> 其他
• 参考文献:

  [1]. Zaitseva NP, et al. Plastic scintillator with effective pulse shape discrimination for neutron and gamma detection. 2016 Apr.

MSDS

Name: Coumarin 2 Laser Grade 99+% (UV-Vis) Material Safety Data Sheet Synonym: 4,6-Dimethyl-7-ethylaminocoumarin ; 2H-1-Benzopyran-2-One,7-(Ethylamino)-4,6-Dimethyl- CAS: 26078-25-1 Section 1 - Chemical Product MSDS Name:Coumarin 2 Laser Grade 99+% (UV-Vis) Material Safety Data Sheet Synonym:4,6-Dimethyl-7-ethylaminocoumarin ; 2H-1-Benzopyran-2-One,7-(Ethylamino)-4,6-Dimethyl- Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 26078-25-1 2H-1-Benzopyran-2-One,7-(Ethylamino)-4 >99 247-446-4 Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 26078-25-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: yellow to yellow-green Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 168 - 170 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: slightly soluble in water Specific Gravity/Density: Molecular Formula: C13H15NO2 Molecular Weight: 217.27 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Dust generation. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 26078-25-1 unlisted. LD50/LC50: Not available. Carcinogenicity: 2H-1-Benzopyran-2-One,7-(Ethylamino)-4,6-Dimethyl- - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 37/39 Wear suitable gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 26078-25-1: No information available. Canada CAS# 26078-25-1 is listed on Canada's DSL List. CAS# 26078-25-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 26078-25-1 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R20/21/22;R36/37/38
• 安全声明 (欧洲): 37/39-26
• WGK德国: -
• 海关编码: 2932209090

海关

海关编码	2932209090
中文概述	2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%