1327-43-1

• 常用中文名：硅酸铝镁盐
• 常用英文名：Silicic acid, aluminum magnesium salt
• CAS号：1327-43-1
• 分子式：Al₂H₆Mg₂O₁₅Si₅
• 分子量：489.03900
• 相关类别： 无机化工 无机盐 硅化物及硅酸盐
• 发布时间：2018-09-26 16:24:58
• 更新时间：2024-01-05 19:19:52

• 良好的乳液稳定剂、悬浮剂。有机胶与硅酸铝镁结合能发挥两者的最佳特性,可用于不同粉状(滑石粉、颜料和药剂)的黏合,是片剂的崩解剂。本品是亲水性胶体,又有假塑性流动性能,是膏霜、乳液、洗发膏、护法用品的黏度改良剂和增稠剂,它可以悬浮和分散粉状颜料,可使产品得到最佳色泽,组织细腻光滑。用作牙膏的增稠剂,可与CMC配合使用,能改进牙膏的触变性和分散性。还具有增稠效应,代替牙膏中1/5~1/2的CMC用量。与天然胶及合成胶的配伍性良好,可改善膏体出条的结构。还能有效地用于药品片剂生产中。在金属和汽车抛光剂、瓷砖和玻璃清洁剂中可悬浮其中的摩擦剂和稳定乳化。用于白鞋油中,悬浮颜料防产品变硬。

名称

• 中文名: 硅酸铝镁盐
• 英文名: veegum
• 英文别名: aluminiummagnesiumsilicate; MangesiumAluminiumMeteSilicate; magnesiumaluminumfluosilicate; Neutralon; Magnesiumaluminosilicate; aluminummagnesiumsilicate; Magnesium aluminum silicate; EINECS 215-478-8

物化性质

• 分子式: Al₂H₆Mg₂O₁₅Si₅
• 分子量: 489.03900
• 精确质量: 487.78800
• PSA: 315.95000
• 稳定性:

  是复合的胶态物质,它的有代表性的化学组成为:二氧化硅61.1%,氧化镁13.7%,氧化铝9.3%,二氧化钛0.1%,氧化铁0.9%,氧化钙2.7%,氧化钠2.9%,氧化钾0.3%,二氧化碳1.8%,结合水7.2%。白色小型片状或粉状,无味无臭,质软而滑爽,含水量小于8%。不溶于水或醇,在水中可膨胀成较原来体积大许多倍的胶态分散体。黏度(5%水分散体)0.25Pa·s±25%。pH值(4%水分散体)约为9。使1g硅酸镁铝的pH减至4,需要0.1mol·L-1HCl6~8mL。硅酸镁铝的膨胀性是可逆的,它能在水中分散,也可以干燥后重新水合,不论次数。它一般用于低固体含量的水分散体中,在广泛的pH范围内稳定。当硅酸镁铝分散于水中时,形成胶态溶胶和凝胶。该水分散体的黏度随含量不同而变化。当含量为1%~2%时其分散体为胶态悬浮体,大于8%时为非透明体,黏度迅速增加,4%~5%时为厚的白色溶胶,当达10%时则形成坚硬的溶胶。硅酸镁铝通常的用量为0.5%~2.5%。硅酸镁铝水分散体具有明显的变性。在配制分散体时,需要适当地加热和适当地延长搅拌时间,才能达到一定的稠度。硅酸镁铝和少量的纤维素胶混合时,能明显地增高黏度,并且长期稳定。硅酸镁铝水分散体遇某些电解质变稠,甚至部分凝聚。

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:4

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积92.2

  7.重原子数量:7

  8.表面电荷:1

  9.复杂度:19.1

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:3

MSDS

Section 1. Chemical Product and Company Identification Magnesium aluminum silicate Common Name/ Trade Name Magnesium aluminum silicate Section 3. Hazards Identification Potential Acute HealthSlightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Effects CARCINOGENIC EFFECTS: Not available. Potential Chronic Health MUTAGENIC EFFECTS: Not available. Effects TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition. Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs. Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product Non-flammable. Auto-Ignition Temperature Not applicable. Flash PointsNot applicable. Not applicable. Flammable Limits Not available. Products of Combustion Fire Hazards in Presence of Not applicable. Various Substances Explosion Hazards inRisks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Presence of Various Substances Fire Fighting MediaNot applicable. and Instructions Not available. Special Remarks on Fire Hazards Special Remarks on Explosion Not available. Hazards Magnesium aluminum silicate Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7. Handling and Storage Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or Precautions the label. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Powder or flakes solid. Granular soli)OdorOdorless. Not available. Taste Not available. Molecular Weight ColorWhite. Off-white. pH (1% soln/water)Not applicable. Boiling PointNot available. Melting PointNot available. Not available. Critical Temperature Specific Gravity2.6 (Water = 1) Not applicable. Vapor Pressure Vapor DensityNot available. VolatilityNot available. Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Not available. Ionicity (in Water) Dispersion PropertiesNot available. Insoluble in cold water. Solubility Magnesium aluminum silicate Section 10. Stability and Reactivity Data The product is stable. Stability Instability TemperatureNot available. Incompatible materials Conditions of Instability Incompatibility with various Reactive with oxidizing agents. substances Non-corrosive in presence of glass. Corrosivity Special Remarks onAvoid powerful oxidizing agents such as fluorine, chlorine trifluoride, manganese triocide adn oxygen Reactivitydifluoride. Special Remarks onNot available. Corrosivity Will not occur. Polymerization Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. Toxicity to AnimalsAcute oral toxicity (LD50): 16000 mg/kg [Rat]. Chronic Effects on Humans Not available. Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Humans Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherAcute Potential Health Effects: Toxic Effects on HumansSkin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: May respiratory tract irritation. Ingestion: Low hazard. Low toxicity. Section 12. Ecological Information Not available. Ecotoxicity BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the ProductsNot available. of Biodegradation Special Remarks on theNot available. Products of Biodegradation Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Magnesium aluminum silicate Section 14. Transport Information DOT ClassificationNot a DOT controlled material (United States). IdentificationNot applicable. Not applicable. Special Provisions for Transport DOT (Pictograms) Section 15. Other Regulatory Information and Pictograms TSCA 8(b) inventory: Magnesium aluminum silicate for CAS no. 1327-43-1; Smectite-group minerals for Federal and State CAS no. 12199-37-0 Regulations CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. Proposition 65 Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsFor CAS no. 1327-43-1: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No. 215-478-8). Canada: Listed on Canadian Domestic Substance List (DSL). China: Listed on National Inventory. Japan: Not listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. For CAS no. 12199-37-0: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No. 235-374-6). Canada: Listed on Canadian Non-Domestic Substance List (NDSL). China: Listed on National Inventory. Japan: Not listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. WHMIS (Canada) Not controlled under WHMIS (Canada). Other Classifications This product is not classifiedNot applicable. DSCL (EEC) according to the EU regulations. Health Hazard HMIS (U.S.A.)1 National Fire Protection 0 Flammability 0 Association (U.S.A.) Fire Hazard 1 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) Magnesium aluminum silicate TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VV8880000 CHEMICAL NAME : Silicic acid, aluminum magnesium salt CAS REGISTRY NUMBER : 1327-43-1 LAST UPDATED : 199701 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >16 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1164,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83046 No. of Facilities: 5916 (estimated) No. of Industries: 71 No. of Occupations: 100 No. of Employees: 110428 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83046 No. of Facilities: 7905 (estimated) No. of Industries: 90 No. of Occupations: 84 No. of Employees: 162965 (estimated) No. of Female Employees: 24342 (estimated)

安全

• 海关编码: 2842100000

制备

将硅酸钠、硫酸铝、食品级氧化镁、铝酸钠及氢氧化钠等原料制成高浓度水溶液,按先后顺序、适当比例加入到反应釜中,边冷却边搅拌,反应一定时间后,压滤、洗涤、干燥,即得成品。

海关

海关编码	2842100000