365-26-4

• 常用中文名：甲基辛弗林盐酸盐
• 常用英文名：Oxilofrine
• CAS号：365-26-4
• 分子式：C₁₀H₁₅NO₂
• 分子量：181.232
• 发布时间：2018-07-01 11:59:12
• 更新时间：2024-01-14 12:42:25

名称

• 中文名: 甲基辛弗林
• 英文名: (R*,S*)-4-hydroxy-α-[1-(methylamino)ethyl]benzyl alcohol
• 中文别名: 奥洛福林; 甲基辛弗林盐酸盐; rac 4-羟基麻黄碱
• 英文别名: METHYLSYNEPHRINE(P); (1RS:2SR)-2-methylamino-1-(4-hydroxy-phenyl)-propanol-(1); p-Hydroxy-a-[1-(methylamino)ethyl]benzyl Alcohol; MethylsyMpatol; a-(1-Methylaminoethyl)-p-hydroxybenzyl Alcohol; Oxilofrine; Benzenemethanol, 4-hydroxy-α-[1-(methylamino)ethyl]-, (R*,S*)-; (+-)-erythro-2-Methylamino-1-(4-hydroxy-phenyl)-propanol-(1); rac 4-Hydroxy Ephedrine; Oxyephedrine; 4-[1-Hydroxy-2-(methylamino)propyl]phenol; 4-Hydroxyephedrine; Benzenemethanol, 4-hydroxy-α-(1-(methylamino)ethyl)-; Oxyephedrin; (±)-4-Hydroxy-α-(1-(methylamino)ethyl)benzyl alcohol; 1-Hydroxypholedrine; Benzenemethanol, 4-hydroxy-α-[1-(methylamino)ethyl]-; Suprifen; Benzyl alcohol, p-hydroxy-α-(1-(methylamino)ethyl)-; (R*,S*)-4-Hydroxy-a-(1-(methylamino)ethyl)benzyl Alcohol; Supriphen; 4-Hydroxy-a-[1-(methylamino)ethyl]benzenemethanol

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 343.8±27.0 °C at 760 mmHg
• 熔点: 152-154°
• 分子式: C₁₀H₁₅NO₂
• 分子量: 181.232
• 闪点: 149.9±14.3 °C
• 精确质量: 181.110275
• PSA: 52.49000
• LogP: 0.32
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.559

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DO6705000 CHEMICAL NAME : Benzyl alcohol, p-hydroxy-alpha-(1-(methylamino)ethyl)- CAS REGISTRY NUMBER : 365-26-4 LAST UPDATED : 198812 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H15-N-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 160,127,1931

合成路线

132224-98-7 ~% 365-26-4

文献：DE547174 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 300

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