493-78-7

• 常用中文名：美沙芬林
• 常用英文名：methaphenilene
• CAS号：493-78-7
• 分子式：C₁₅H₂₀N₂S
• 分子量：260.39800
• 发布时间：2018-02-26 08:00:00
• 更新时间：2024-01-09 15:33:55

名称

• 中文名: 美沙芬林
• 英文名: N,N-dimethyl-N'-phenyl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine
• 英文别名: N,N-dimethyl-N'-phenyl-N'-[2]thienylmethyl-ethylenediamine; ETHYLENEDIAMINE,N,N-DIMETHYL-N'-PHENYL-N'-2-THENYL; W 50 Base; Methaphenilene [INN:BAN]; Metafenileno [INN-Spanish]; Diatrin; 1,2-Ethanediamine,N,N-dimethyl-N'-phenyl-N'-(2-thienylmethyl); Methaphenilen; Diatrin Base; Methaphenilenum [INN-Latin]; Metafenilene [DCIT]; N,N-Dimethyl-N'-phenyl-N'-[2]thienylmethyl-aethylendiamin

物化性质

• 密度: 1.111g/cm3
• 沸点: 377.4ºC at 760 mmHg
• 分子式: C₁₅H₂₀N₂S
• 分子量: 260.39800
• 闪点: 182ºC
• 精确质量: 260.13500
• PSA: 34.72000
• LogP: 3.31630
• 蒸汽压: 6.78E-06mmHg at 25°C
• 折射率: 1.608

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KV4550000 CHEMICAL NAME : Ethylenediamine, N,N-dimethyl-N'-phenyl-N'-2-thenyl- CAS REGISTRY NUMBER : 493-78-7 BEILSTEIN REFERENCE NO. : 0208014 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H20-N2-S MOLECULAR WEIGHT : 260.43 WISWESSER LINE NOTATION : T5SJ B1NR&2N1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 117 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,388,1949

合成路线

765-50-4 ~% 493-78-7

文献：Kyrides et al. Journal of the American Chemical Society, 1947 , vol. 69, p. 2239 Full Text View citing articles Show Details Monsanto Chem. Co. Patent: US2457048 , 1946 ;

74497-02-2 ~% 493-78-7

文献：Leonard; Solmssen Journal of the American Chemical Society, 1948 , vol. 70, p. 2064,2066

6711-46-2 ~% 493-78-7

文献：Leonard; Solmssen Journal of the American Chemical Society, 1948 , vol. 70, p. 2064,2066