4876-14-6

• 常用中文名：2-氨基-3-(2-氧代-1,2-二氢喹啉-4-基)丙酸盐酸盐
• 常用英文名：2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride
• CAS号：4876-14-6
• 分子式：C₁₂H₁₃ClN₂O₃
• 分子量：268.696
• 相关类别： 研究领域 其他
• 发布时间：2018-12-27 18:19:50
• 更新时间：2024-01-08 16:45:01
• 2-氨基-3-(2-氧代-1,2-二氢喹啉-4-基)丙酸盐酸盐是丙氨酸衍生物[1]。

名称

• 中文名: 2-氨基-3-(2-氧代-1,2-二氢喹啉-4-基)丙酸盐酸盐
• 英文名: DL-3-(1,2-Dihydro-2-Oxo-Quinoline-4-yl)Alanine Hydrochloride
• 中文别名: 2-氨基-3-[2(1H)-喹啉酮-4-基]-丙酸盐酸盐; 2-氨基-3-(1,2-二氢-2-氧喹啉-4-基)丙酸盐酸盐
• 英文别名: 3-(2-Oxo-1,2-dihydroquinolin-4-yl)alanine hydrochloride (1:1); MFCD03839816; 3-(2-Oxo-1,2-dihydro-4-quinolinyl)alanine hydrochloride (1:1); 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, (αS)-, hydrochloride (1:1); 3-(2-Oxo-1,2-dihydroquinolin-4-yl)-L-alanine hydrochloride (1:1); 4-Quinolinepropanoic acid, α-amino-1,2-dihydro-2-oxo-, hydrochloride (1:1); 3-(2-Oxo-1,2-dihydro-4-quinolinyl)-L-alanine hydrochloride (1:1); DL-3-(1,2-Dihydro-2-oxo-quinoline-4-yl)alanine hydrochloride; 2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride; 2-AMINO-3-(1, 2-DIHYDRO-2-OXO-4-QUINOLYL)PROPIONIC ACID HYDROCHLORIDE

物化性质

• 沸点: 522.7ºC at 760mmHg
• 熔点: 225 °C
• 分子式: C₁₂H₁₃ClN₂O₃
• 分子量: 268.696
• 闪点: 269.9ºC
• 精确质量: 268.061462
• PSA: 96.18000
• LogP: 1.98480
• 外观性状: 固体;White to Almost white powder to crystal
• 储存条件: 0-10°C;存放于惰性气体之中;避免湿气 (吸湿),加热

生物活性

• 描述: 2-氨基-3-(2-氧代-1,2-二氢喹啉-4-基)丙酸盐酸盐是丙氨酸衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1117.

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 2-Amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid, HCl Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:2-Amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid, HCl CAS number:4876-14-6 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C12H12N2O3.ClH Molecular weight:268.7 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

4900-38-3 ~87% 4876-14-6

文献：Uchida; Tabusa; Komatsu; Morita; Kanbe; Nakagawa Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3775 - 3786

4876-10-2 ~% 4876-14-6

文献：Uchida; Tabusa; Komatsu; Morita; Kanbe; Nakagawa Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3775 - 3786

上下游产品

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4900-38-3 4876-10-2
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海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%