1009-35-4

• 常用中文名：3-硝基-4-氟苯腈
• 常用英文名：4-Fluoro-3-nitrobenzonitrile
• CAS号：1009-35-4
• 分子式：C₇H₃FN₂O₂
• 分子量：166.11
• 相关类别： 有机原料 烃类化合物及其衍生物 烃类硝化物
• 发布时间：2018-09-28 13:38:22
• 更新时间：2024-01-02 13:14:09
• 4-氟-3-硝基苯是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

名称

• 中文名: 3-硝基-4-氟苯腈
• 英文名: 4-Fluoro-3-nitrobenzonitrile
• 中文别名: 4-氟-3-硝基苯甲腈
• 英文别名: 4-Cyano-1-fluoro-2-nitrobenzene; MFCD01632197; WNR BF ECN; Benzonitrile, 4-fluoro-3-nitro-; 4-Fluoro-3-nitrobenzonitrile

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 277.6±25.0 °C at 760 mmHg
• 熔点: 90.5-91.5ºC
• 分子式: C₇H₃FN₂O₂
• 分子量: 166.11
• 闪点: 121.7±23.2 °C
• 精确质量: 166.017853
• PSA: 69.61000
• LogP: 0.90
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.553
• 储存条件: 2~8℃

生物活性

• 描述: 4-氟-3-硝基苯是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。
• 相关类别:
  研究领域 >> 其他
• 体外研究: 4-氟-3-硝基苯甲腈用作医药中间体。也用作合成和精细化工中间体。

MSDS

Material Safety Data Sheet Section1. Identification of the substance 4-Fluoro-3-nitrobenzonitrile Product Name: Synonyms:5-Cyano-5-fluoro-1-nitrobenzene Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. H314:Causes severe skin burns and eye damage P280:Wear protective gloves/protective clothing/eye protection/face protection P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing P310:Immediately call a POISON CENTER or doctor/physician Section3. Composition/information on ingredients. Ingredient name:4-Fluoro-3-nitrobenzonitrile CAS number:1009-35-4 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage This product should be handled only by, or under the close supervision of, those properly qualified Handling: in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula: C7H3FN2O2 Molecular weight: 166.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information UN Number:UN3261 Class: 8 Packing group: II Proper shipping name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (4-Fluoro-3-nitrobenzonitrile) Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): 26-36/37/39
• 危险品运输编码: UN 3439
• 海关编码: 2926909090

合成路线

1194-02-1 ~89% 1009-35-4

文献：Aridoss, Gopalakrishnan; Laali, Kenneth K. Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 8088 - 8094

939-80-0 ~75% 1009-35-4

文献：Deutsch; Niclas Synthetic Communications, 1991 , vol. 21, # 4 p. 505 - 513

42564-51-2 ~99% 1009-35-4

文献：Augustine, John Kallikat; Atta, Rajendra Nath; Ramappa, Balakrishna Kolathur; Boodappa, Chandrakantha Synlett, 2009 , # 20 p. 3378 - 3382

939-80-0 ~57% 3272-08-0 1009-35-4

文献：Tetrahedron, , vol. 55, # 25 p. 7725 - 7738

939-80-0 ~29% 3272-08-0 1009-35-4 64248-62-0

文献：Tetrahedron, , vol. 55, # 25 p. 7725 - 7738

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%