392-22-3

392-22-3结构式

常用中文名：2-氯-6-氟肉桂酸
常用英文名：3-(2-Chloro-6-fluorophenyl)acrylic acid
CAS号：392-22-3
分子式：C₉H₆ClFO₂
分子量：200.59400
相关类别：香精与香料合成香料芳香肉桂酸、酯及衍生物
发布时间：2018-07-01 19:11:09
更新时间：2024-01-23 09:00:38

化源商城直购

中文名	2-氯-6-氟肉桂酸
英文名	2-chloro-6-fluorocinnamic acid
中文别名	2-氯-6-氟肉桂酸,PREDOMINANTLY TRANS
英文别名	2-Chloro-6-fluorocinnamic acid,predominantly trans 2-Chloro-6-fluorocinnamicacid 6-Fluor-2-chlor-trans-zimtsaeure RARECHEM BK HW 0069 MFCD00051582 6-fluoro-2-chloro-trans-cinnamic acid 2-Chloro-6-fluorocinnamic acid

密度	1.42g/cm3
沸点	312.8ºC at 760mmHg
熔点	165-169 °C(lit.)
分子式	C₉H₆ClFO₂
分子量	200.59400
闪点	143ºC
精确质量	200.00400
PSA	37.30000
LogP	2.57690
折射率	1.604
储存条件	室温
分子结构	1、摩尔折射率：48.59 2、摩尔体积（m³/mol）：141.1 3、等张比容（90.2K）：375.0 4、表面张力（dyne/cm）：49.7 5、极化率（10 ^-24cm ³）：19.26
更多	一、物性数据性状：灰白色结晶粉末密度（g/mL,25/4℃）：不可用相对蒸汽密度（g/mL,空气=1）：不可用熔点（ºC）： 165-169 沸点（ºC,常压）：不可用沸点（ºC,5.2kPa）：不可用折射率：不可用闪点（ºC）：不可用比旋光度（º）：不可用自燃点或引燃温度（ºC）：不可用蒸气压（kPa,25ºC）：不可用饱和蒸气压（kPa,60ºC）：不可用燃烧热（KJ/mol）：不可用临界温度（ºC）：不可用临界压力（KPa）：不可用油水（辛醇/水）分配系数的对数值：不可用爆炸上限（%,V/V）：不可用爆炸下限（%,V/V）：不可用溶解性：不溶于水

Name:	2-Chloro-6-fluorocinnamic acid 98% Material Safety Data Sheet
Synonym:
CAS:	392-22-3

Section 1 - Chemical Product MSDS Name:2-Chloro-6-fluorocinnamic acid 98% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
392-22-3	2-Chloro-6-fluorocinnamic acid	98%	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 392-22-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 163 - 165 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density:
Molecular Formula: C9H6ClFO2
Molecular Weight: 200.6

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 392-22-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-Chloro-6-fluorocinnamic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 392-22-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 392-22-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 392-22-3 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

毒理学数据:

二、毒理学数据：

急性毒性：不可用。

生态学数据:

三、生态学数据：

1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	S26-S37/39
WGK德国	3
海关编码	2916399090

141-82-2

387-45-1

392-22-3

文献：Saeed, Aamer; Mahesar, Parvez Ali; Zaib, Sumera; Khan, Muhammad Siraj; Matin, Abdul; Shahid, Mohammad; Iqbal, Jamshed European Journal of Medicinal Chemistry, 2014 , vol. 78, p. 43 - 53

443-83-4

392-22-3

文献：Willstaedt Chemische Berichte, 1931 , vol. 64, p. 2688,2692

海关编码	2916399090
中文概述	2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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