上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：化合物Ascaridole
纯度：99.66%
规格：
联系人：徐经理
联系电话：13311869306

湖北魏氏化学试剂股份有限公司
湖北省武汉市洪山区
产品名：阿斯利多
纯度：98.0%
规格：5mg/25mg/10g/50g
联系人：张栋
联系电话：18717199209

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512-85-6生产厂家

512-85-6价格

512-85-6

512-85-6结构式

常用中文名：阿斯利多
常用英文名：Ascaridole
CAS号：512-85-6
分子式：C₁₀H₁₆O₂
分子量：168.23
相关类别：研究领域心血管疾病
发布时间：2018-07-08 18:05:35
更新时间：2024-01-08 22:12:29
Ascaridole是一种驱虫药,也具有抗疟活性[1]。

化源商城直购

中文名	阿斯利多
英文名	ascaridole
英文别名	Ascaridiol 1-methyl-4-propan-2-yl-2,3-dioxabicyclo[2.2.2]oct-5-ene Askaridol 1,4-Peroxy-p-menth-2-ene Ascarisin 1,4-epidioxy-p-menth-2-ene Ascaridol cis-Ascaridole 1,4-Peroxido-p-menthene-2 ASCARIDOLE Ascaridole0 nnDiscontiuned Unable to ship Ascaricum 1-methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene

描述	Ascaridole是一种驱虫药,也具有抗疟活性[1]。
相关类别	研究领域 >> 感染
参考文献	[1]. Pollack, et al. The effect of ascaridole on the in vitro development ofPlasmodium falciparum . Parasitol Res 76, 570–572 (1990).

密度	1.051 g/cm3
沸点	172.3ºC at 760 mmHg
熔点	3.3ºC
分子式	C₁₀H₁₆O₂
分子量	168.23
闪点	55.9ºC
精确质量	168.11500
PSA	18.46000
LogP	2.45170
折射率	1.498
储存条件	库房通风低温干燥,轻装轻卸,与有机物、还原剂、硫、磷易燃物分开存放
稳定性	1. 存在于烟叶中。 2. 致癌活性弱。
分子结构	1、摩尔折射率：48.83 2、摩尔体积（cm³/mol）：162.6 3、等张比容（90.2K）：413.1 4、表面张力（dyne/cm）：41.5 5、极化率（10-24cm3）：19.36
计算化学	1.疏水参数计算参考值（XlogP）:2.3 2.氢键供体数量:0 3.氢键受体数量:2 4.可旋转化学键数量:1 5.互变异构体数量:无 6.拓扑分子极性表面积18.5 7.重原子数量:12 8.表面电荷:0 9.复杂度:222 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:2 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1. 性状：不稳定液体，加热或以有机酸处理易爆炸。 2. 溶解性：不溶于水，溶于乙醇、丙酮、苯，微溶于氯仿。 3. 沸点（ºC）：39~40(266.6pa) 4. 熔点（ºC）：3.3 5. 闪点（ºC）：55.9 6. 相对密度(d²⁰₄₎：1.0103 7.折射率_(n²⁰_D) ：1.4769

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OT0175000

CHEMICAL NAME :: p-Menth-2-ene, 1,4-epidioxy-

CAS REGISTRY NUMBER :: 512-85-6

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H16-O2

MOLECULAR WEIGHT :: 168.26

WISWESSER LINE NOTATION :: T66 A B AO BO DUTJ CY F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,1,1961 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 7,252,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 7,252,1948

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 24,359,1925 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 gm/kg/42W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 35,707,1965

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38 gm/kg/63W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: 14JTAF "Mycotoxins in Foodstuffs, Proceedings of the Symposium held at the Massachusetts Institute of Technology, 1964," Wogan, G.N., ed., Cambridge, MA, MIT Press, 1965 Volume(issue)/page/year: -,275,1965

海关编码	2932999099

99-86-5

~97%

512-85-6

文献：Ribeiro, Sonia M.; Serra, Armenio C.; Rocha Gonsalves, A.M.d'A. Tetrahedron, 2007 , vol. 63, # 33 p. 7885 - 7891

99-86-5

~76%

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文献：Jary, Walther G.; Ganglberger, Thorsten; Poechlauer, Peter; Falk, Heinz Monatshefte fur Chemie, 2005 , vol. 136, # 4 p. 537 - 541

99-87-6

512-85-6

文献：Nardello, Veronique; Herve, Melanie; Alsters, Paul L.; Aubry, Jean-Marie Advanced Synthesis and Catalysis, 2002 , vol. 344, # 2 p. 184 - 191

99-86-5

~36%

104975-22-6

512-85-6

文献：Nitz, Siegfried; Kollmannsberger, Hubert; Spraul, Martin H.; Drawert, Friedrich Phytochemistry (Elsevier), 1989 , vol. 28, # 11 p. 3051 - 3054

99-86-5

~38%

104975-22-6

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99-87-6

文献：Nitz, Siegfried; Kollmannsberger, Hubert; Spraul, Martin H.; Drawert, Friedrich Phytochemistry (Elsevier), 1989 , vol. 28, # 11 p. 3051 - 3054

99-86-5

~90%

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114564-48-6

133213-20-4

详细

文献：Matusch, Rudolf; Schmidt, Gerhard Angewandte Chemie, 1988 , vol. 100, # 5 p. 729 - 730

67-56-1

99-86-5

512-85-6

文献：Schenck; Gollnick Journal de Chimie Physique et de Physico-Chimie Biologique, 1958 , vol. 55, p. 892

99-86-5

807306-71-4

67-63-0

512-85-6

文献：Schenck et al. Justus Liebigs Annalen der Chemie, 1953 , vol. 584, p. 125,149 Full Text Show Details Schering A. G. Patent: DE752437 , 1941 ; DRP/DRBP Org.Chem. Full Text Show Details Schenck; Ziegler Naturwissenschaften, 1944 , vol. 32, p. 157

99-86-5

15086-94-9

67-63-0

512-85-6

上游产品 6
99-86-5 99-87-6 67-56-1 807306-71-4
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海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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