53370-90-4

• 常用中文名：依沙酰胺
• 常用英文名：Exalamide
• CAS号：53370-90-4
• 分子式：C₁₃H₁₉NO₂
• 分子量：221.29500
• 相关类别： 原料药 人工合成抗感染类药 抗病毒类药
• 发布时间：2018-02-09 08:00:00
• 更新时间：2024-07-12 18:34:32
• Exalamide是一种抗真菌剂。

名称

• 中文名: 依沙酰胺
• 英文名: exalamide
• 中文别名: 已氧苯酰胺
• 英文别名: 2-n-Hexyloxybenzamide; 2-hexyloxybenzamide; 2-(Hexyloxy)benzamide; Exalamidum; Hyperan; Exalamida; o-Hexyloxybenzamide; 2-hexoxybenzamide; 2-hexyloxy-benzoic acid amide; 2-Hexyloxy-benzoesaeure-amid

物化性质

• 密度: 1.03 g/cm3
• 沸点: 356.9ºC at 760 mmHg
• 熔点: 72-74ºC
• 分子式: C₁₃H₁₉NO₂
• 分子量: 221.29500
• 闪点: 149.1ºC
• 精确质量: 221.14200
• PSA: 52.32000
• LogP: 3.44490
• 外观性状: 白色粉末
• 折射率: 1.517
• 储存条件: Refrigerator

生物活性

• 描述: Exalamide是一种抗真菌剂。
• 相关类别:
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 感染

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CV5050000 CHEMICAL NAME : Benzamide, o-hexyloxy- CAS REGISTRY NUMBER : 53370-90-4 BEILSTEIN REFERENCE NO. : 2645003 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C13-H19-N-O2 MOLECULAR WEIGHT : 221.33 WISWESSER LINE NOTATION : ZVR BO6 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 530 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >15 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 13210 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 650 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >15 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,100,1982

安全

• 海关编码: 2924299090

合成路线

201230-82-2 105474-59-7 ~54% 53370-90-4

文献：Nielsen, Dennis U.; Taaning, Rolf H.; Lindhardt, Anders T.; Gogsig, Thomas M.; Skrydstrup, Troels Organic Letters, 2011 , vol. 13, # 16 p. 4454 - 4457

上下游产品

上游产品  2
201230-82-2 105474-59-7
下游产品  0

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%