51372-29-3

• 常用中文名：布地奈德
• 常用英文名：Budesonide
• CAS号：51372-29-3
• 分子式：C₂₅H₃₄O₆
• 分子量：430.534
• 相关类别： 原料药 激素及调节内分泌功能类药 肾上腺皮质激素类药
• 发布时间：2018-02-04 08:00:00
• 更新时间：2024-01-08 15:52:45

名称

• 中文名: 布地奈德
• 英文名: 16a(R),17-(Butylidenebis(oxy))-11b,21-dihydroxypregna-1,4-diene-3,20-dione
• 中文别名: 布地奈德-22R
• 英文别名: Budesonide; Spirocort; Bidien; arachidonic acid ethanolamide; 2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(2-hydroxyacetyl)-4a,6a-dimethyl-8-propyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-; N-arachidonoylethanolamide; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-Hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-on; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacétyl)-4a,6a-diméthyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodécahydro-2H-naphto[2',1':4,5]indéno[1,2-d][1,3]dioxol-2-one; Pulmicort; Rhinocort; 2H-naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-, (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-; N-Arachidonoyl-2-hydroxyethylamide; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; Budeson; arachidonylethanolamide; 2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(2-hydroxyacetyl)-4a,6a-dimethyl-8-propyl-, (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-; ENTOCORT; dexbudesonide; (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; 2H-naphth[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-; 5,8,11,14-Eicosatetraenoylethanolamide; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; N-arachidonoyl ethanolamine; arachidonoylethanolamide; Arachidonoyl-EA; 16a(R),17-(Butylidenebis(oxy))-11b,21-dihydroxy-pregna-1,4-diene-3,20-dione

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 599.7±50.0 °C at 760 mmHg
• 熔点: 194-199ºC
• 分子式: C₂₅H₃₄O₆
• 分子量: 430.534
• 闪点: 201.8±23.6 °C
• 精确质量: 430.235535
• PSA: 93.06000
• LogP: 3.14
• 外观性状: 淡米色固体
• 蒸汽压: 0.0±3.9 mmHg at 25°C
• 折射率: 1.592
• 储存条件: -20°C Freezer

安全

• 危害码 (欧洲): Xi
• 海关编码: 2914509090

合成路线

123-72-8 638-94-8 ~99% 51372-29-3

文献：SUN PHARMACEUTICAL INDUSTRIES LIMITED Patent: WO2005/44759 A2, 2005 ; Location in patent: Page/Page column 11 ;

13951-70-7 123-72-8 ~% 51372-29-3

文献：Lenna, Roberto; Montoro, Maurizio Patent: US2009/259037 A1, 2009 ; Location in patent: Page/Page column 3-4 ;

上下游产品

上游产品  3
123-72-8 638-94-8 13951-70-7
下游产品  0

海关

海关编码	2914509090
中文概述	2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%