664362-16-7

• 常用中文名：3-乙炔基哌啶-1-甲酸叔丁酯
• 常用英文名：tert-butyl 3-ethynylpiperidine-1-carboxylate
• CAS号：664362-16-7
• 分子式：C₁₂H₁₉NO₂
• 分子量：209.28500
• 发布时间：2018-06-26 17:50:05
• 更新时间：2024-01-20 22:09:25

名称

• 中文名: 3-乙炔基哌啶-1-甲酸叔丁酯
• 英文名: tert-butyl 3-ethynylpiperidine-1-carboxylate
• 中文别名: 3-乙炔-1-哌啶羧酸-1,1-二甲基乙酯
• 英文别名: 1-BOC-3-ethynylpiperidine; 3-ethynyl-piperidine-1-carboxylic acid tert-butyl ester; 1-Piperidinecarboxylic acid,3-ethynyl-,1,1-dimethylethyl ester

物化性质

• 密度: 1.02
• 沸点: 269.583ºC at 760 mmHg
• 分子式: C₁₂H₁₉NO₂
• 分子量: 209.28500
• 精确质量: 209.14200
• PSA: 29.54000
• LogP: 2.20460
• 折射率: 1.491
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

851882-50-3 ~94% 664362-16-7

文献：ADDEX PHARMACEUTICALS SA Patent: WO2005/44797 A1, 2005 ; Location in patent: Page/Page column 54 ; WO 2005/044797 A1

90965-06-3 118156-93-7 ~76% 664362-16-7

文献：Bourrain, Sylvie; Hunt, Peter Alan; Huscroft, Ian Thomas; Kulagowski, Janusz Jozef; London, Clare; Naylor, Elizabeth Mary; Raubo, Piotr Antoni; Seward, Eileen Mary Patent: US2004/229864 A1, 2004 ; Location in patent: Page/Page column 11 ; US 20040229864 A1

118156-93-7 27491-70-9 ~98% 664362-16-7

文献：Astar Biotech LLC; YU, Chunrong; Huang, Haihong; Zhang, Dongfeng; Li, Peng Patent: US2014/31354 A1, 2014 ; Location in patent: Paragraph 0296; 0421; 0422 ;