72653-14-6

• 常用中文名：4-乙酰基-4-乙氧基羰基庚二酸
• 常用英文名：4-Acetyl-4-(ethoxycarbonyl)heptanedioic acid
• CAS号：72653-14-6
• 分子式：C₁₂H₁₈O₇
• 分子量：274.26700
• 发布时间：2018-12-17 19:11:23
• 更新时间：2024-01-04 17:48:15

名称

• 中文名: 4-乙酰基-4-乙氧基羰基庚二酸
• 英文名: 4-acetyl-4-ethoxycarbonylheptanedioic acid
• 英文别名: 4-Acetyl-4-aethoxycarbonyl-pimelinsaeure; 4-ACETYL-4-(ETHOXYCARBONYL)HEPTANEDIOIC ACID; 4-acetyl-4-(ethoxycarbonyl)pimelic acid

物化性质

• 密度: 1.266g/cm3
• 沸点: 504.5ºC at 760 mmHg
• 熔点: 105ºC
• 分子式: C₁₂H₁₈O₇
• 分子量: 274.26700
• 闪点: 191.1ºC
• 精确质量: 274.10500
• PSA: 117.97000
• LogP: 0.85450
• 折射率: 1.489
• 储存条件: 室温，干燥

MSDS

Name: 4-Acetyl-4-(ethoxycarbonyl)heptanedioic acid 97% Material Safety Data Sheet Synonym: Ethyl 2,2-bis(2-carboxyethyl)acetoacetat CAS: 72653-14-6 Section 1 - Chemical Product MSDS Name:4-Acetyl-4-(ethoxycarbonyl)heptanedioic acid 97% Material Safety Data Sheet Synonym:Ethyl 2,2-bis(2-carboxyethyl)acetoacetat Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 72653-14-6 4-Acetyl-4-(ethoxycarbonyl)heptanedioi 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 72653-14-6: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 105 - 108 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H18O7 Molecular Weight: 274 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, acrid smoke and fumes. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 72653-14-6 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Acetyl-4-(ethoxycarbonyl)heptanedioic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 72653-14-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 72653-14-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 72653-14-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S37/39
• 海关编码: 2918990090

合成路线

1135619-58-7 ~% 72653-14-6

文献：WO2007/71966 A1, ; Page/Page column 60 ; WO 2007/071966 A1

72948-75-5 ~% 72653-14-6

文献：Helvetica Chimica Acta, , vol. 62, p. 2802 - 2816

141-97-9 ~% 72653-14-6

文献：Helvetica Chimica Acta, , vol. 62, p. 2802 - 2816

1112-25-0 ~% 72653-14-6

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2180 - 2183

上下游产品

上游产品  4
1135619-58-7 72948-75-5 141-97-9 1112-25-0
下游产品  4
20277-40-1 23062-53-5 773-34-2 81687-78-7

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%