3704-09-4

• 常用中文名：米勃龙
• 常用英文名：Mibolerone
• CAS号：3704-09-4
• 分子式：C₂₀H₃₀O₂
• 分子量：302.45100
• 相关类别： 原料药 激素及调节内分泌功能类药 雄激素及同化激素类药
• 发布时间：2018-08-23 09:32:28
• 更新时间：2024-01-07 12:11:40
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名称

• 中文名: 米勃龙
• 英文名: mibolerone
• 中文别名: 米勃酮
• 英文别名: MIBOLERONE; U-10,997; Miboleron; CDB 904; Miboleronum; [3H]-Mibolerone; MFCD00221774; (7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one; Cheque; Mibolerona; EINECS 223-046-5

物化性质

• 密度: 1.1g/cm3
• 沸点: 440.5ºC at 760mmHg
• 熔点: 168-171ºC
• 分子式: C₂₀H₃₀O₂
• 分子量: 302.45100
• 闪点: 187.8ºC
• 精确质量: 302.22500
• PSA: 37.30000
• LogP: 4.12520
• 外观性状: 白色结晶固体
• 折射率: 1.553
• 储存条件: Controlled Substance, -20?C Freezer

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KG7980000 CHEMICAL NAME : Estr-4-en-3-one, 17-beta-hydroxy-7-alpha,17-dimethyl- CAS REGISTRY NUMBER : 3704-09-4 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C20-H30-O2 MOLECULAR WEIGHT : 302.50 WISWESSER LINE NOTATION : L E5 B666 OVTJ E1 FQ F1 K1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 8985 ug/kg/9.6Y-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Reproductive - Tumorigenic effects - ovarian tumors REFERENCE : TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,177,1985 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 800 ug/kg SEX/DURATION : female 10 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : STEDAM Steroids. (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609) V.1- 1963- Volume(issue)/page/year: 9,235,1967 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 196 ug/kg SEX/DURATION : female 6-61 day(s) after conception lactating female 42 day(s) post-birth TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - urogenital system REFERENCE : AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 39,837,1978

安全

• 符号: GHS08
• 信号词: Danger
• 危害声明: H360
• 警示性声明: P201-P308 + P313
• 危害码 (欧洲): T
• 风险声明 (欧洲): 60-63
• 安全声明 (欧洲): 36-45
• 危险品运输编码: NONH for all modes of transport