572-09-8

• 常用中文名：2,3,4,6-四乙酰氧基-alpha-D-吡喃葡萄糖溴化物
• 常用英文名：2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide
• CAS号：572-09-8
• 分子式：C₁₄H₁₉BrO₉
• 分子量：411.20
• 相关类别： 生物化工 糖类化合物 单糖
• 发布时间：2018-06-17 18:33:41
• 更新时间：2024-01-02 20:06:37
• α-乙酰溴葡萄糖是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

名称

• 中文名: 乙酰溴-α-D-葡萄糖
• 英文名: 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide
• 中文别名: 2,3,4,6-四乙酰氧基-α-D-吡喃葡萄糖溴化物; 乙酰溴-Alpha-D-葡萄糖; 溴代葡萄糖苷; 2,3,4,6-四-O-乙酰基-α-D-吡喃葡萄糖酰溴; 乙酰溴代葡萄糖; 2,3,4,6-四乙酰氧基-alpha-D-吡喃葡萄糖溴化物
• 英文别名: 1-Bromo-a-D-glucose Tetraacetate; MFCD00063254; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-bromotetrahydro-2H-pyran-3,4,5-triyl triacetate; a-D-Glucopyranosyl Bromide 2,3,4,6-Tetraacetate; EINECS 209-339-0; 2,3,4,6-Tetraacetyl-a-D-glucopyranosyl Bromide; α-D-Glucopyranosyl bromide, tetraacetate; a-D-Acetobromoglucose; a-Bromoglucose Tetraacetate; 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl bromid; 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl bromide; a-Acetobromoglucose; 2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 412.0±45.0 °C at 760 mmHg
• 熔点: 83-88ºC
• 分子式: C₁₄H₁₉BrO₉
• 分子量: 411.20
• 闪点: 203.0±28.7 °C
• 精确质量: 410.021240
• PSA: 114.43000
• LogP: 2.05
• 外观性状: 白色粉末
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.503
• 储存条件:

  1.充氩气密封避光于-18℃干燥保存。

• 稳定性:

  要避免的物料：氧化物，水分，潮湿。

  要分解的产品：一氧化碳和二氧化碳，溴化氢。

• 分子结构:

  1、 摩尔折射率：81.61

  2、 摩尔体积（cm³/mol）：275.9

  3、 等张比容（90.2K）：726.2

  4、 表面张力（dyne/cm）：47.9

  5、 极化率（10^-24cm³）：32.35

• 计算化学:

  1、 疏水参数计算参考值（XlogP）：1.5

  2、 氢键供体数量：0

  3、 氢键受体数量：9

  4、 可旋转化学键数量：9

  5、 拓扑分子极性表面积（TPSA）：114

  6、 重原子数量：24

  7、 表面电荷：0

  8、 复杂度：507

  9、 同位素原子数量：0

  10、 确定原子立构中心数量：5

  11、 不确定原子立构中心数量：0

  12、 确定化学键立构中心数量：0

  13、 不确定化学键立构中心数量：0

  14、 共价键单元数量：1

• 更多:

  1. 性状：白色到黄色结晶或粉末。对光敏感。遇水分解。

  2. 密度（g/mL,25/4℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：88-89

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º，c=3,氯仿中）：+199.3

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 油水（辛醇/水）分配系数的对数值：未确定

  16. 临界压力（KPa）：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定 19.溶解性：较多溶于甲醇，易溶于乙醚、氯仿、丙酮、乙酸乙酯和苯，微溶于石油醚。

生物活性

• 描述: α-乙酰溴葡萄糖是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他

MSDS

2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide Revision number: 5 (stabilized with CaCO3) SAFETY DATA SHEET Section1. IDENTIFICATION 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) Product name: Revision number:5 Section2. HAZARDS IDENTIFICATION GHS classification Not classified PHYSICAL HAZARDS HEALTH HAZARDSNot classified Not classified ENVIRONMENTAL HAZARDS GHS label elements, including precautionary statements None Pictograms or hazard symbols Signal wordNo signal word None Hazard statements Precautionary statements:None Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) Percent:>98.0%(T) CAS Number:572-09-8 Chemical Formula:C14H19BrO9 Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, water spray, carbon dioxide. media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) Section5. FIRE-FIGHTING MEASURES Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. When extinguishing fire, be sure to wear personal protective equipment. Special protective equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a freezer. Store under inert gas. Protect from moisture. Store away from incompatible materials such as oxidizing agents. Heat-sensitive, Light-sensitive, Moisture-sensitive Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Install a closed system or local exhaust as possible so that workers should not be Engineering controls: exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Eye protection:Safety glasses. A face-shield, if the situation requires. Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Form:Crystal- Powder Colour:White - Slightly pale yellow Odour:No data available pH: No data available Melting point/freezing point:89°C No data available Boiling point/range: Flash point:No data available Flammability or explosive limits: No data available Lower: Upper:No data available No data available Relative density: Solubility(ies): [Water]No data available 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) Section9. PHYSICAL AND CHEMICAL PROPERTIES No data available [Other solvents] Section10. STABILITY AND REACTIVITY Chemical stability:Stable under proper conditions. Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Hydrogen bromide products: Section11. TOXICOLOGICAL INFORMATION No data available Acute Toxicity: Skin corrosion/irritation: No data available No data available Serious eye damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: No data available IARC = NTP =No data available No data available Reproductive toxicity: Section12. ECOLOGICAL INFORMATION Ecotoxicity: Fish:No data available Crustacea:No data available Algae:No data available Persistence / degradability: No data available BioaccumulativeNo data available potential(BCF): Mobility in soil Log Pow:No data available Soil adsorption (Koc):No data available Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations UN-No:Not listed Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S24/25
• 危险品运输编码: NONH for all modes of transport
• WGK德国: -
• 海关编码: 29329985

合成路线

上下游产品

上游产品  9
604-69-3 2280-44-6 108-24-7 604-68-2
83-87-4 492-62-6 6378-65-0 112-17-4
4163-65-9
下游产品  9
108124-75-0 105088-14-0 474-58-8 4098-06-0
498-07-7 709-50-2 3323-72-6 3366-47-0
38081-37-7

海关

海关编码	29329985