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20977-50-8

20977-50-8结构式
20977-50-8结构式
  • 常用中文名:卡哌隆
  • 常用英文名:Carperone
  • CAS号:20977-50-8
  • 分子式:C19H27FN2O3
  • 分子量:350.42800
  • 发布时间:2018-09-28 18:38:22
  • 更新时间:2024-01-06 09:39:08

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中文名 卡哌隆
英文名 [1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] N-propan-2-ylcarbamate
英文别名 CARBAMIC ACID,ISOPROPYL-,1-(3-(p-FLUOROBENZOYL)PROPYL)PIPERID-4-YL ESTER
Carperona [INN-Spanish]
Carperonum
1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate
Carperonum [INN-Latin]
AL-1021
Carperone
(1-Methylethyl)carbamic acid,1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester
1-(4-fluoro-phenyl)-4-(4-isopropylcarbamoyloxy-piperidin-1-yl)-butan-1-one
Carperona
密度 1.15g/cm3
沸点 493.7ºC at 760mmHg
分子式 C19H27FN2O3
分子量 350.42800
闪点 252.4ºC
精确质量 350.20100
PSA 62.13000
LogP 3.52990
蒸汽压 6.85E-10mmHg at 25°C
折射率 1.533

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FB3235000
CHEMICAL NAME :
Carbamic acid, isopropyl-, 1-(3-(p-fluorobenzoyl)propyl)piperid-4-yl ester
CAS REGISTRY NUMBER :
20977-50-8
BEILSTEIN REFERENCE NO. :
1551021
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C19-H27-F-N2-O3
MOLECULAR WEIGHT :
350.48
WISWESSER LINE NOTATION :
T6NTJ A3VR DF& DOVMY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
2140 ug/kg
TOXIC EFFECTS :
Behavioral - rigidity (including catalepsy) Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section
REFERENCE :
CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 11,779,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
265 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,184,1972

海关编码 2933399090
海关编码 2933399090
中文概述 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%