123359-43-3

• 常用中文名：百里酚单磷酸二钠盐 水合物
• 常用英文名：Thymolphthalein monophosphate disodium hydrate
• CAS号：123359-43-3
• 分子式：C₂₈H₃₁Na₂O₈P
• 分子量：572.49400
• 相关类别： 信号通路 代谢酶/蛋白酶 磷酸酶
• 发布时间：2018-06-26 19:02:05
• 更新时间：2024-01-11 22:04:17
• 一磷酸胸腺酚酞二钠水合物是测定酸性磷酸酶和碱性磷酸酶的显色底物。胸腺酞在反应过程中释放,增加介质的pH值以便于检测,产生颜色并停止水解。一磷酸胸腺酞二钠水合物可用于血清中前列腺磷酸酶的特异性检测[1][2]。

名称

• 中文名: 百里酚酞单磷酸二钠盐三水合物
• 英文名: Thymolphthalein monophosphoric acid disodium salt trihydrate
• 中文别名: 百里酚酞单磷酸二钠盐
• 英文别名: thymolphthalein monophosphate disodium salt hydrate; thymolphthalein monophosphate disodium salt n-hydrate; thymolphthalein monophosphoric acid disodium salt xh2o; thymolphthalein monophosphoric acid,dis odium salt hydrate

物化性质

• 沸点: 683.3ºC at 760mmHg
• 分子式: C₂₈H₃₁Na₂O₈P
• 分子量: 572.49400
• 闪点: 367.1ºC
• 精确质量: 572.15500
• PSA: 137.99000
• LogP: 7.00170
• 蒸汽压: 1.31E-19mmHg at 25°C
• 储存条件:

  密封，在0ºC下保存

• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：572.155194 Da

  8、标称质量：572 Da

  9、平均质量：572.4942 Da

• 更多:

  1. 性状：未确定

  2. 密度（g/mL,20℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,KPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（Pa,20ºC）：未确定

  12. 饱和蒸气压（KPa,20ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

生物活性

• 描述: 一磷酸胸腺酚酞二钠水合物是测定酸性磷酸酶和碱性磷酸酶的显色底物。胸腺酞在反应过程中释放,增加介质的pH值以便于检测,产生颜色并停止水解。一磷酸胸腺酞二钠水合物可用于血清中前列腺磷酸酶的特异性检测[1][2]。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 磷酸酶
  研究领域 >> 其他
• 参考文献:

  [1]. Roy AV, et al. Sodium thymolphthalein monophosphate: a new acid phosphatase substrate with greater specificity for the prostatic enzyme in serum. Clin Chem. 1971 Nov;17(11):1093-102

  [2]. Morin LG. Ammonium thymolphthalein monophosphate as a new substrate for alkaline and acid phosphatase determinations in serum. Clin Chem. 1973 Oct;19(10):1135-8.

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: Thymolphthalein monophosphate disodium salt hydrate Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Thymolphthalein monophosphate disodium salt hydrate CAS number:123359-43-3 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C28H29O7P.2Na.H2O Molecular weight:572.5 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 安全声明 (欧洲): S22-S24/25