16752-54-8

• 常用中文名：2-(甲基氨基)丙腈
• 常用英文名：2-(Methylamino)propanenitrile
• CAS号：16752-54-8
• 分子式：C₄H₈N₂
• 分子量：84.11970
• 发布时间：2018-02-27 08:00:00
• 更新时间：2024-01-09 12:12:10

名称

• 中文名: 2-(甲基氨基)丙腈
• 英文名: 2-(Methylamino)propanenitrile
• 中文别名: 2-(甲氨基)丙腈
• 英文别名: N-Methyl-DL-alanin-nitril; N-cyanoethyl-N-methylamine; DL-2-Methylamino-propionsaeure-nitril; methylaminopropionitrile; DL-2-Methylamino-propionitril; N-methyl-DL-alanine nitrile

物化性质

• 密度: 0.865g/cm3
• 沸点: 157.2ºC at 760mmHg
• 分子式: C₄H₈N₂
• 分子量: 84.11970
• 闪点: 48.9ºC
• 精确质量: 84.06870
• PSA: 35.82000
• LogP: 0.50878
• 蒸汽压: 2.79mmHg at 25°C
• 折射率: 1.409

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 2-(Methylamino)propanenitrile Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:2-(Methylamino)propanenitrile CAS number:16752-54-8 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C4H8N2 Molecular weight:84.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TZ4905000 CHEMICAL NAME : Propanenitrile, 2-(methylamino)- CAS REGISTRY NUMBER : 16752-54-8 LAST UPDATED : 199806 DATA ITEMS CITED : 4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 48 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545552 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1990 mg/m3/1H TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545810 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 50100 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Liver - other changes Blood - other changes REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545552

安全

• 海关编码: 2926909090

合成路线

143-33-9 593-51-1 75-07-0 ~89% 16752-54-8

文献：Zoete, Vincent; Bailly, Fabrice; Catteau, Jean-Pierre; Bernier, Jean-Luc Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 20 p. 2983 - 2988

151-50-8 75-07-0 74-89-5 ~% 16752-54-8

文献：Spence,T.W.M.; Tennant,G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 97 - 102

74-90-8 75-07-0 74-89-5 ~% 16752-54-8

文献：I.G. Farbenind. Patent: DE694808 , 1935 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 78

74-89-5 ~% 16752-54-8

文献：du Pont de Nemours and Co. Patent: US2328940 , 1941 ;

78-97-7 74-89-5 ~% 16752-54-8

文献：Kurtz,P.; Disselnkoetter,H. Justus Liebigs Annalen der Chemie, 1972 , vol. 764, p. 69 - 93

57-12-5 75-07-0 124-40-3 ~% 16752-54-8

文献：Taillades, Jacques Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 1 p. 89 - 100

7732-18-5 593-51-1 75-07-0 ~% 16752-54-8

文献：Luten Journal of Organic Chemistry, 1938 , vol. 3, p. 590,594 Full Text Show Details Asscher Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 967 Full Text Show Details Cocker; Lapworth; Walton Journal of the Chemical Society, 1930 , p. 453 Full Text Show Details Cocker; Lapworth; Peters Journal of the Chemical Society, 1931 , p. 1391 Full Text Show Details Biilmann; Berg Bulletin de la Societe Chimique de France, 1934 , vol. <5>1, p. 1658

上下游产品

上游产品  10
143-33-9 593-51-1 75-07-0 151-50-8
74-89-5 74-90-8 78-97-7 57-12-5
124-40-3 7732-18-5
下游产品  4
57768-53-3 78-97-7 600-21-5 32012-16-1

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%