81919-14-4

• 常用中文名：苄达赖氨酸
• 常用英文名：Bendazac L-lysine
• CAS号：81919-14-4
• 分子式：C₂₂H₂₈N₄O₅
• 分子量：428.482
• 相关类别： 生物化工 常见氨基酸及蛋白质类药
• 发布时间：2018-10-04 17:09:26
• 更新时间：2024-01-02 11:04:07
• Bendazac L-Lysine 是用来控制白内障的药物之一,可以保护患者的视力水平,从而延缓手术干预的需要。

名称

• 中文名: 苄达赖氨酸
• 英文名: Bendazac L-lysine
• 中文别名: 赖氨酸-((1-苄基-1H-吲唑-3-基)氧)乙酸; 卞达赖氨酸
• 英文别名: L-Lysine-(1-benzyl-1H-indazol-3-yloxy)acetic acid; BENDAZAC LYSINE UV; L-Lysine, compd. with 2-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]acetic acid (1:1); BENDAZAC L-LYSINE SALT; Bendazac lysine; Bendazac lysine (ban); L-Lysine, ((1-(phenylmethyl)-1H-indazol-3-yl)oxy)acetate; BENDAZAC LYSINE 2H2O; Bendalina (tn); (2S)-2,6-Diammoniohexanoate [(1-benzyl-1H-indazol-3-yl)oxy]acetate; L-Lysine, mono(((1-(phenylmethyl)-1H-indazol-3-yl)oxy)acetate)

物化性质

• 沸点: 698.4ºC at 760 mmHg
• 熔点: 178-181ºC
• 分子式: C₂₂H₂₈N₄O₅
• 分子量: 428.482
• 闪点: 376.2ºC
• 精确质量: 428.205963
• PSA: 153.69000
• LogP: 3.47590
• 外观性状: 白色
• 储存条件: 2-8℃

生物活性

• 描述: Bendazac L-Lysine 是用来控制白内障的药物之一,可以保护患者的视力水平,从而延缓手术干预的需要。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
• 参考文献:

  [1]. Yin XX, et al. Protective effects of bendazac lysine on early experimental diabetic nephropathy in rats.

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: Bendazac L-lysine Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:Bendazac L-lysine CAS number:81919-14-4 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C16H14N2O3.C6H14N2O2 Molecular weight:428.5 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OL5673000 CHEMICAL NAME : L-Lysine, mono(((1-(phenylmethyl)-1H-indazol-3-yl)oxy)acetate), dihydrate CAS REGISTRY NUMBER : 81919-14-4 LAST UPDATED : 198910 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C16-H14-N2-O3.C6-H14-N2-O2.2H2-O MOLECULAR WEIGHT : 464.58 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3100 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 19,649,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 19,649,1983

安全

• 海关编码: 2942000000

海关

海关编码	2942000000