433-48-7

• 常用中文名：Propanoic acid,3-fluoro-2-oxo-
• 常用英文名：Propanoic acid,3-fluoro-2-oxo-
• CAS号：433-48-7
• 分子式：C₃H₃FO₃
• 分子量：106.05300
• 发布时间：2017-06-04 23:35:32
• 更新时间：2024-01-12 07:51:52

名称

• 英文名: 3-fluoropyruvic acid
• 英文别名: fluoropyruvate; 3-Fluoro-2-oxopropanoic acid; 3-fluoropyruvate; Propanoic acid,3-fluoro-2-oxo-; 3-Fluoropyruvic acid; 2-Oxo-3-fluoropropionic acid; fluoropyruvic acid; 3-fluoro-2-oxo-propionic acid

物化性质

• 密度: 1.409g/cm3
• 沸点: 174.9ºC at 760mmHg
• 分子式: C₃H₃FO₃
• 分子量: 106.05300
• 闪点: 59.6ºC
• 精确质量: 106.00700
• PSA: 54.37000
• 蒸汽压: 0.566mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UZ0900000 CHEMICAL NAME : Pyruvic acid, 3-fluoro CAS REGISTRY NUMBER : 433-48-7 BEILSTEIN REFERENCE NO. : 1746780 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C3-H3-F-O3 MOLECULAR WEIGHT : 106.06 WISWESSER LINE NOTATION : QNU1V1F HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 173,126,1954 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,48,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 173,126,1954

安全

• 海关编码: 2918300090

合成路线

392-58-5 ~% 433-48-7

文献：Nair; Busch Journal of Organic Chemistry, 1958 , vol. 23, p. 137 Full Text View citing articles Show Details Blank et al. Journal of the Chemical Society, 1955 , p. 2190,2192 Bl. Res. Coun. Israel, 1953 , vol. 3, p. 101

97935-40-5 ~% 433-48-7

文献：Tsushima, Tadahiko; Kawada, Kenji Tetrahedron Letters, 1985 , vol. 26, # 20 p. 2445 - 2448

392-58-5 ~% 433-48-7 392-47-2

文献：Brandaenge, Svante; Dahlman, Olof; Mahlen, Anders; Moerch, Lars Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 1 p. 67 - 70

97643-52-2 ~% 433-48-7

文献：Schummer, Anita; Yu, Hongtao; Simon, Helmut Tetrahedron, 1991 , vol. 47, # 43 p. 9019 - 9034

16652-37-2 ~% 433-48-7 35455-21-1

文献：Seo, Young-Man; Khang, Yong-Ho; Yun, Hyungdon Bioscience, Biotechnology and Biochemistry, 2011 , vol. 75, # 4 p. 820 - 822

16652-37-2 ~% 433-48-7 35455-21-1 35455-20-0 详细

文献：Goncalves, Luciana P. B.; Antunes; Oestreicher, Enrique G. Organic Process Research and Development, 2006 , vol. 10, # 3 p. 673 - 677

上下游产品

上游产品  2
392-58-5 16652-37-2
下游产品  7
35455-20-0 127-17-3 35455-21-1 35523-45-6
51033-95-5 399-87-1 401-48-9

海关

海关编码	2918300090
中文概述	2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%