191729-44-9

• 常用中文名：通关藤苷I
• 常用英文名：Tenacissoside I
• CAS号：191729-44-9
• 分子式：C₄₄H₆₂O₁₄
• 分子量：814.955
• 相关类别： 天然产物 甾体化合物
• 发布时间：2018-07-06 17:02:10
• 更新时间：2024-01-05 14:31:09
• Tenacissoside I 是一种来自 Marsdenia tenacissima 的 C21 甾体,在 M. tenacissima 含量较高。

名称

• 中文名: 通关藤苷I
• 英文名: (3β,5α,11α,12β,14β,17α)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoate
• 中文别名: 通关藤苷I; 通关藤皂苷I
• 英文别名: (3β,5α,11α,12β,14β)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoate; Pregnan-20-one, 12-(acetyloxy)-11-(benzoyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-, (3β,5α,11α,12β,14be ta,17α)-; Pregnan-20-one, 12-(acetyloxy)-11-(benzoyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-, (3β,5α,11α,12β,14β)-; (1R,3aR,4aS,6aS,8S,10aS,10bS,11S,12S,12aS)-12-acetoxy-1-acetyl-8-(((2R,4R,5R,6R)-5-(((2S,3R,4R,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl benzoate; (3β,5α,11α,12β,14β,17α)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl benzoa te; Tenacissoside I

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 850.8±65.0 °C at 760 mmHg
• 分子式: C₄₄H₆₂O₁₄
• 分子量: 814.955
• 闪点: 247.2±27.8 °C
• 精确质量: 814.413940
• PSA: 178.04000
• LogP: 5.34
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.580
• 储存条件: 2-8C

生物活性

• 描述: Tenacissoside I 是一种来自 Marsdenia tenacissima 的 C21 甾体,在 M. tenacissima 含量较高。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Zhao C, et al, Metabolic profiling of tenacigenin B, tenacissoside H and tenacissoside I using UHPLC-ESI-Orbitrap MS/MS. Biomed Chromatogr. 2016 Nov;30(11):1757-1765.

  [2]. Wang W, et al. Simultaneous quantification of two steroidal glycosides after oral gavage of Marsdenia tenacissima extract in rats using a LC-MS/MS method. Biomed Chromatogr. 2015 Apr;29(4):633-40.