前往化源商城

品牌现货直购
供应商:我要出现这里







查看所有供应商和价格请点击:

60-70-8生产厂家

60-70-8价格

60-70-8

60-70-8结构式
60-70-8结构式

化源商城直购

中文名 黎芦碱
英文名 Veratramine
中文别名 藜芦胺
(2S,3R,5S)-5-甲基-2-[(1S)-1-[(3S,6AR,11AS,11BR)-2,3,4,6,6A,11,11A,11B-八氢-3-羟基-10,11B-二甲基-1H-苯并[A]芴-9-基]乙基]-3-哌啶醇
藜芦铵
黎芦胺
英文别名 Veratramine
(3β,23R)-14,15,16,17-Tetradehydroveratraman-3,23-diol
Vreaframine
(3b,23b)-14,15,16,17-Tetradehydroveratraman-3,23-diol
3-Piperidinol, 5-methyl-2-[(1S)-1-[(3S,6aR,11aS,11bR)-2,3,4,6,6a,11,11a,11b-octahydro-3-hydroxy-10,11b-dimethyl-1H-benzo[a]fluoren-9-yl]ethyl]-, (2S,3R,5S)-
Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3β,23β)-
veratraMin
密度 1.1±0.1 g/cm3
沸点 565.0±50.0 °C at 760 mmHg
熔点 122-124ºC
分子式 C27H39NO2
分子量 409.604
闪点 86.2±20.7 °C
精确质量 409.298065
PSA 52.49000
LogP 4.90
外观性状 固体;White to Light yellow powder to crystal
蒸汽压 0.0±1.6 mmHg at 25°C
折射率 1.601
储存条件 <0°C;避免加热
水溶解性 水溶性:微溶;可溶于:甲醇,醇,苯,氯仿

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YX5094000
CHEMICAL NAME :
Veratramine
CAS REGISTRY NUMBER :
60-70-8
BEILSTEIN REFERENCE NO. :
0055515
LAST UPDATED :
199706
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C27-H39-N-O2
MOLECULAR WEIGHT :
409.67
WISWESSER LINE NOTATION :
L D6 B566 LU&TTTJ A1 E1 OQ FY1&- BT6MTJ CQ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4500 ug/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,89,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 2,418,1953
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
33 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 3,175,1970 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
16700 ug/kg
SEX/DURATION :
female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 136,1174,1971
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
29 mg/kg
SEX/DURATION :
female 13-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 123,921,1966 *** REVIEWS *** TOXICOLOGY REVIEW LYPHAD Lyon Pharmaceutique. (Medipharly, 12, rue de la Barre, 69002 Lyons, France) V.1- 1950- Volume(issue)/page/year: 26,5,1975