116970-50-4

• 常用中文名：N-(2-氨基乙基)-5-异喹啉磺酰胺盐酸盐
• 常用英文名：N-(2-Aminoethyl)isoquinoline-5-sulfonamide hydrochloride
• CAS号：116970-50-4
• 分子式：C₁₁H₁₃N₃O₂S
• 分子量：251.30500
• 发布时间：2017-09-30 00:25:45
• 更新时间：2024-08-09 14:16:37

名称

• 中文名: N-(2-氨乙基)-5-异喹啉磺酰胺盐酸盐
• 英文名: h-9
• 英文别名: H-9,DiHCl

物化性质

• 沸点: 479.8ºC at 760mmHg
• 熔点: 250-255ºC (dec)
• 分子式: C₁₁H₁₃N₃O₂S
• 分子量: 251.30500
• 闪点: 243.9ºC
• 精确质量: 251.07300
• PSA: 93.46000
• LogP: 2.64380
• 外观性状: 白色结晶固体
• 蒸汽压: 2.3E-09mmHg at 25°C
• 储存条件: 室温，保存在惰性气体中

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NX4897000 CHEMICAL NAME : 5-Isoquinolinesulfonamide, N-(2-aminoethyl)-, monohydrochloride CAS REGISTRY NUMBER : 116970-50-4 LAST UPDATED : 199312 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H13-N3-O2-S.Cl-H MOLECULAR WEIGHT : 287.79 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-264030 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 190 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-264030

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26

合成路线

107-15-3 105627-79-0 ~71% 116970-50-4

文献：Morikawa; Sone; Asano Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 46 - 50

27655-40-9 ~% 116970-50-4

文献：Journal of Medicinal Chemistry, , vol. 32, # 1 p. 46 - 50

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