29098-15-5

• 常用中文名：特罗芬那酯
• 常用英文名：terofenamate
• CAS号：29098-15-5
• 分子式：C₁₇H₁₇Cl₂NO₃
• 分子量：354.22800
• 发布时间：2018-08-27 12:35:49
• 更新时间：2024-01-13 20:41:30

名称

• 中文名: 特罗芬那酯
• 英文名: ethoxymethyl 2-(2,6-dichloro-3-methylanilino)benzoate
• 英文别名: Terofenamato [INN-Spanish]; Etofen; Etoclofene; EINECS 249-434-4; Terofenamate; N-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl ester; M-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl ester; Ethoxymethyl N-(2,6-dichloro-m-tolyl)anthranilate; Terofenamatum [INN-Latin]

物化性质

• 密度: 1.297g/cm3
• 沸点: 439ºC at 760 mmHg
• 分子式: C₁₇H₁₇Cl₂NO₃
• 分子量: 354.22800
• 闪点: 219.3ºC
• 精确质量: 353.05900
• PSA: 47.56000
• LogP: 5.26920
• 蒸汽压: 6.6E-08mmHg at 25°C
• 折射率: 1.597

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CB2975100 CHEMICAL NAME : Anthranilic acid, N-(2,6-dichloro-m-tolyl)-, ethoxymethyl ester CAS REGISTRY NUMBER : 29098-15-5 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C17-H17-Cl2-N-O3 MOLECULAR WEIGHT : 354.25 WISWESSER LINE NOTATION : GR CG D1 BMR BVO1O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 307 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - cough REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 274 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - cough REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 918 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6240 mg/kg/26W-I TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in leukocyte (WBC) count Related to Chronic Data - death REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 115,41,1976

安全

• 海关编码: 2922509090

合成路线

644-62-2 3188-13-4 ~% 29098-15-5

文献：Salimbeni; Manghisi; Magistretti Farmaco, Edizione Scientifica, 1975 , vol. 30, # 4 p. 276 - 286

上下游产品

上游产品  2
644-62-2 3188-13-4
下游产品  0

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%