5431-33-4

• 常用中文名：丙烯酸-2,3-环氧丙酯十八烯酸
• 常用英文名：glycidyl oleate
• CAS号：5431-33-4
• 分子式：C₂₁H₃₈O₃
• 分子量：338.525
• 发布时间：2018-12-25 10:35:56
• 更新时间：2024-01-11 11:07:08

名称

• 中文名: 丙烯酸-2,3-环氧丙酯十八烯酸
• 英文名: oxiran-2-ylmethyl (Z)-octadec-9-enoate
• 中文别名: 油酸缩水甘油酯
• 英文别名: Glycidol oleate; (rac)-(+/-)-2-(oleoyloxymethyl)oxirane; 9-Octadecenoic acid, oxiranylmethyl ester, (9Z)-; Oleic acid glycidyl ester; glycidyl oleate; 2,3-Epoxypropyl oleate; Oleic acid,2,3-epoxypropyl ester; Glycidyl octadecenoate; Oxiran-2-ylmethyl (9Z)-octadec-9-enoate; 2,3-Epoxy-1-propanol oleate; 2-(oleoyloxymethyl)oxirane; 2,3-Epoxypropyl ester of oleic acid; Oxiranylmethyl ester of 9-octadecenoic acid; 2-Oxiranylmethyl (9Z)-9-octadecenoate; (+-)-Oelsaeure-(2,3-epoxy-propylester)

物化性质

• 密度: 0.9±0.1 g/cm3
• 沸点: 430.3±28.0 °C at 760 mmHg
• 分子式: C₂₁H₃₈O₃
• 分子量: 338.525
• 闪点: 163.7±8.9 °C
• 精确质量: 338.282104
• PSA: 38.83000
• LogP: 8.21
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.472

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RK0700000 CHEMICAL NAME : Oleic acid, 2,3-epoxypropyl ester CAS REGISTRY NUMBER : 5431-33-4 LAST UPDATED : 199710 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C21-H38-O3 MOLECULAR WEIGHT : 338.59 WISWESSER LINE NOTATION : T3OTJ B1OV8U9 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3520 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 8 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1040 mg/kg/52W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - leukemia MUTATION DATA TEST SYSTEM : Rodent - rat DOSE/DURATION : 1 gm/kg REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,235,1951 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,183,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,183,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0777 No. of Facilities: 84 (estimated) No. of Industries: 2 No. of Occupations: 10 No. of Employees: 1746 (estimated)

合成路线

112-77-6 556-52-5 ~88% 5431-33-4

文献：Stamatov, Stephan D.; Stawinski, Jacek Tetrahedron, 2005 , vol. 61, # 15 p. 3659 - 3669

112-80-1 556-52-5 ~72% 5431-33-4

文献：Tanaka, Ryo; Kato, Masaru; Suzuki, Takahiro; Nakazaki, Atsuo; Nozaki, Emi; Gotoh, Mari; Murakami-Murofushi, Kimiko; Kobayashi, Susumu Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4180 - 4182

112-62-9 556-52-5 ~% 5431-33-4

文献：Haines, Troy D.; Adlaf, Kevin J.; Pierceall, Robert M.; Lee, Inmok; Venkitasubramanian, Padmesh; Collison, Mark W. JAOCS, Journal of the American Oil Chemists' Society, 2011 , vol. 88, # 1 p. 1 - 14

143-19-1 106-89-8 ~% 5431-33-4

文献：Journal of Organic Chemistry, , vol. 8, p. 550,554

上下游产品

上游产品  6
112-77-6 556-52-5 112-80-1 112-62-9
143-19-1 106-89-8
下游产品  2
3443-84-3 1716-07-0