艾地骨化醇

更新时间：2024-01-02 10:30:02

艾地骨化醇结构式	常用名	艾地骨化醇	英文名	Eldecalcitol
	CAS号	104121-92-8	分子量	490.715
	密度	1.1±0.1 g/cm3	沸点	655.7±55.0 °C at 760 mmHg
	分子式	C₃₀H₅₀O₅	熔点	126-128ºC
	MSDS	N/A	闪点	350.3±31.5 °C

艾地骨化醇用途

Eldecalcitol(ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3)是1,25-二羟基维生素D3的类似物。

中文名	1α,25-二羟基-2β-(3-羟基丙氧基)维生素D3
英文名	(1S,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol
中文别名	2-(3-羟基丙氧基)-1,25-二羟基维他命D3 \| 2-(3-羟基丙氧基)-1,25-二羟基维他命D3 \| 艾地骨化醇
英文别名	更多

描述	Eldecalcitol(ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3)是1,25-二羟基维生素D3的类似物。
相关类别	信号通路 >> 维生素 D 相关 >> VD/VDR 研究领域 >> 其他
参考文献	[1]. Matsumoto T.Osteoporosis Treatment by a New Active Vitamin D3 Compound, Eldecalcitol, in Japan.Curr Osteoporos Rep. 2012 Aug 24. [2]. Shiraki M, et al. Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.Curr Med Res Opin. 2012 Aug 23. [3]. Matsumoto T, Endo I.Eldecalcitol for the treatment of osteoporosis.Drugs Today (Barc). 2012 Mar;48(3):189-96. [4]. Sakai S, et al.Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength.Bone. 2012 May;50(5):1054-63. Epub 2012 Feb 17. [5]. Sanford M, McCormack PL.Spotlight on eldecalcitol in osteoporosis.Drugs Aging. 2012 Jan 1;29(1):69-71.

描述

Eldecalcitol(ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3)是1,25-二羟基维生素D3的类似物。

相关类别

信号通路 >> 维生素 D 相关 >> VD/VDR

研究领域 >> 其他

参考文献

[1]. Matsumoto T.Osteoporosis Treatment by a New Active Vitamin D3 Compound, Eldecalcitol, in Japan.Curr Osteoporos Rep. 2012 Aug 24.

[2]. Shiraki M, et al. Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.Curr Med Res Opin. 2012 Aug 23.

[3]. Matsumoto T, Endo I.Eldecalcitol for the treatment of osteoporosis.Drugs Today (Barc). 2012 Mar;48(3):189-96.

[4]. Sakai S, et al.Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength.Bone. 2012 May;50(5):1054-63. Epub 2012 Feb 17.

[5]. Sanford M, McCormack PL.Spotlight on eldecalcitol in osteoporosis.Drugs Aging. 2012 Jan 1;29(1):69-71.

密度	1.1±0.1 g/cm3
沸点	655.7±55.0 °C at 760 mmHg
熔点	126-128ºC
分子式	C₃₀H₅₀O₅
分子量	490.715
闪点	350.3±31.5 °C
精确质量	490.365814
PSA	90.15000
LogP	5.84
蒸汽压	0.0±4.5 mmHg at 25°C
折射率	1.550
储存条件	2-8℃

艾地骨化醇上游产品 8
CAS号342645-84-5 (1β,2α,3α,5Z,7E... CAS号342644-91-1 [3R-(1Z,3β,4α,5... CAS号342645-07-2 (1α,2β,3β,5Z,7E... CAS号66774-80-9 Inhoffen Lythgo...
CAS号200636-54-0 [3R-(1Z,3β,4α,5... CAS号244278-87-3 [3R-(1Z,3β,4α,5... CAS号377091-68-4 [3R-(1Z,3β,4α,5... CAS号342644-83-1 [3R-(1Z,3β,4α,5...
艾地骨化醇下游产品 0

HY-A0020

ED 71

9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, 2-(3-hydroxypropoxy)-, (1α,2β,3β,5Z,7E)-

UNII-I2JP8UE90H

Eldecalcitol

CS-0363

1,3-Cyclohexanediol, 2-(3-hydroxypropoxy)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,2R,3R,5Z)-

1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3

(1R,2R,3R,5Z,7E)-2-(3-Hydroxypropoxy)-9,10-secocholesta-5,7,10-triene-1,3,25-triol